Moore B S, Hyde J S, Manaligod L M
Ann Allergy. 1977 Oct;39(4):240-5.
Among 115 children and young adults studied, 52 had current and 25 had past household exposure to dogs, totaling 77 subjects. Of 53 with clinical hypersensitivity to dog, 32 had a history of exposure, 34 positive cutaneous reactions and 15 RAST positive results. Of 62 without clinical hypersensitivity, 45 had a history of household exposure, 24 positive cutaneous reactions and 6 RAST positive results. Cutaneous tests were not done on seven individuals. The major type of clinical symptomatology to dogs was ocular and nasal, 40 of 53. Thirty-two of 53 patients developed asthma exacerbations alone, or in combination with other manifestations, upon dog exposure. Dermal reactions were urticaria is six and contact eczema in two subjects. RAST inhibition results suggested that in vitro testing may be more useful when allergens from specific dog breed extracts are characterized.
在研究的115名儿童和年轻人中，52人目前家中养狗，25人过去家中养狗，共计77名受试者。在53名对狗有临床过敏反应的人中，32人有接触史，34人皮肤反应呈阳性，15人RAST检测呈阳性。在62名无临床过敏反应的人中，45人有家庭接触史，24人皮肤反应呈阳性，6人RAST检测呈阳性。7人未进行皮肤试验。对狗的主要临床症状类型为眼部和鼻部症状，53人中有40人出现此类症状。53名患者中有32人在接触狗后单独或与其他表现一起出现哮喘加重。皮肤反应中，6人出现荨麻疹，2人出现接触性湿疹。RAST抑制试验结果表明，当对特定犬种提取物中的过敏原进行鉴定时，体外检测可能更有用。
