Maeda Y, Akiyama K, Hayakawa T, Hasegawa M, Kaneko F, Shida T, Miyamoto T
National Sagamihara Hospital, Research Center for Rheumato-Allergology.
Arerugi. 1993 Jan;42(1):9-17.
We studied adult asthmatics who were sensitized (RAST sore > or = 1) by cats and dogs allergens. Compared with non-sensitized asthmatics, the following some characteristics were noted in the sensitized asthmatics: 1) The histogram of the onset age of asthma showed two peaks. 2) The asthmatics sensitized by cats epithelium were more frequent and had higher RAST scores than those sensitized by dog hair dander. 3) There was a significant correlation between the RAST scores to dogs dander and dog hair. 4) There was no correlation between the RAST score to cat epithelium and dog hair. 5) The positive rations of intradermal testing to other allergens were higher in the sensitized asthmatics than in the non-sensitized asthmatics, especially to some foods allergens. 6) The asthmatics sensitized by cat and dog allergens were much more sensitized by house-dust mites than were the non-sensitized asthmatics. The asthmatics sensitized by cat and dog demonstrated being allergic to not only cat and dog allergens but also to many other allergens. We thought that the sensitized asthmatics were more atopic than the non-sensitized asthmatics and this was the reason why they were sensitized by cat and dog. The RAST scores to cat allergens were higher than the RAST scores to dog allergens. This fact showed that the cat was more important than the dog. This result agreed with our clinical experience.
我们研究了对猫和狗过敏原致敏（放射性变应原吸附试验[RAST]评分≥1）的成年哮喘患者。与未致敏的哮喘患者相比，在致敏的哮喘患者中观察到以下一些特征：1）哮喘发病年龄的直方图显示有两个峰值。2）与对狗毛皮屑致敏的哮喘患者相比，对猫上皮致敏的哮喘患者更常见且RAST评分更高。3）对狗皮屑和狗毛的RAST评分之间存在显著相关性。4）对猫上皮和狗毛的RAST评分之间无相关性。5）致敏哮喘患者对其他过敏原的皮内试验阳性率高于未致敏的哮喘患者，尤其是对某些食物过敏原。6）对猫和狗过敏原致敏的哮喘患者比对未致敏的哮喘患者对屋尘螨的致敏程度要高得多。对猫和狗致敏的哮喘患者不仅对猫和狗过敏原过敏，而且对许多其他过敏原也过敏。我们认为致敏的哮喘患者比未致敏的哮喘患者更具有特应性，这就是他们对猫和狗致敏的原因。对猫过敏原的RAST评分高于对狗过敏原的RAST评分。这一事实表明猫比狗更重要。这一结果与我们的临床经验相符。
