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印度社会阶层与心脏调查中高血压的患病率及决定因素

Prevalence and determinants of hypertension in the Indian social class and heart survey.

作者信息

Singh R B, Sharma J P, Rastogi V, Niaz M A, Singh N K

机构信息

Heart Research Laboratory, Medical Hospital and Research Centre, Moradabad, India.

出版信息

J Hum Hypertens. 1997 Jan;11(1):51-6. doi: 10.1038/sj.jhh.1000384.

Abstract

To determine the association of socio-economic status (SES) and prevalence of hypertension and its risk factors in a rural population, a cross sectional survey was conducted in two randomly selected villages in the Moradabad district in North India. There were 1935 residents aged over 25 (984 men and 951 women) who were randomly selected and categorised into social classes 1-4 depending upon SES based on occupation, housing conditions, land holding, total per capita income, ownership of consumer durables and education. The prevalence of hypertension diagnosed by JNC V criteria (>140/90 mm Hg) was significantly higher among social class 1 and 2 and showed positive relation with SES in both sexes. Among social class 1 and 2 subjects, there was a higher prevalence of overweight and obesity and sedentary lifestyle. Logistic regression analysis with adjustment of age showed that SES had a positive relation with hypertension (odds ratio: men 1.09, 95% CI 1.05-1.14; women 1.08, 95% CI 1.05-1.13), body mass index (odds ratio: men 1.12, 1.08-1.18; women 1.11, 1.06-1.16) and sedentary lifestyle (odds ratio: men 1.45, 1.32-1.58; women 1.38, 1.26-1.49). Only weak but significant associations were observed with smoking, alcohol and salt intake. The association of hypertension with social class was reduced after adjustment of body mass index, sedentary lifestyle, smoking and salt intake (odds ratio: men 0.96, 0.81-1.14; women 0.73, 0.54-1.04). There was an increase in the prevalence of hypertension and age-specific blood pressure (BP) with increasing age in both sexes. The overall prevalence of hypertension by WHO criteria (>160/95) was 4.6% and by JNC V criteria 20.8%, and the rates were comparable in both sexes. Social class 1 and 2 subjects in rural North India have a higher prevalence of hypertension and its risk factors of overweight and sedentary lifestyle.

摘要

为了确定印度北部莫拉达巴德地区农村人口的社会经济地位(SES)与高血压患病率及其危险因素之间的关联,在该地区随机选取的两个村庄开展了一项横断面调查。共有1935名年龄超过25岁的居民(984名男性和951名女性)被随机选取,并根据职业、住房条件、土地拥有量、人均总收入、耐用消费品拥有情况和教育程度等SES因素分为1 - 4个社会阶层。按照美国国家联合委员会第5版(JNC V)标准(收缩压>140/舒张压>90 mmHg)诊断出的高血压患病率在第1和第2社会阶层中显著更高,且在男女两性中均与SES呈正相关。在第1和第2社会阶层的受试者中,超重、肥胖和久坐不动生活方式的患病率更高。对年龄进行调整后的逻辑回归分析表明,SES与高血压(优势比:男性1.09,95%置信区间1.05 - 1.14;女性1.08,95%置信区间1.05 - 1.13)、体重指数(优势比:男性1.12,1.08 - 1.18;女性1.11,1.06 - 1.16)以及久坐不动生活方式(优势比:男性1.45,1.32 - 1.58;女性1.38,1.26 - 1.49)呈正相关。仅观察到与吸烟、饮酒和盐摄入量存在微弱但显著的关联。在对体重指数、久坐不动生活方式、吸烟和盐摄入量进行调整后,高血压与社会阶层之间的关联减弱(优势比:男性0.96,0.81 - 1.14;女性0.73,0.54 - 1.04)。随着年龄增长,男女两性的高血压患病率和特定年龄的血压(BP)均有所上升。按照世界卫生组织(WHO)标准(收缩压>160/舒张压>95)诊断出的高血压总体患病率为4.6%,按照JNC V标准为20.8%,且两性患病率相当。印度北部农村地区第1和第2社会阶层的受试者高血压患病率及其超重和久坐不动生活方式等危险因素的患病率更高。

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