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印度生活方式与心脏研究中北印度城市人口的社会阶层与冠状动脉疾病

Social class and coronary artery disease in a urban population of North India in the Indian Lifestyle and Heart Study.

作者信息

Singh R B, Niaz M A, Thakur A S, Janus E D, Moshiri M

机构信息

Centre of Nutrition, Medical Hospital and Research Centre, Moradabad-10, India.

出版信息

Int J Cardiol. 1998 Apr 1;64(2):195-203. doi: 10.1016/s0167-5273(98)00048-5.

Abstract

OBJECTIVE

To determine the association of social class with prevalence of coronary risk factors and coronary artery disease (CAD).

DESIGN AND SETTING

Total community cross sectional survey of 20 randomly selected streets in the city of Moradabad.

SUBJECTS AND METHODS

1806 urban (904 men and 902 women) randomly selected subjects aged 25-64 years. The survey methods were physician and dietitian administered questionnaire, physical examination and electrocardiography. All subjects were divided into social classes 1-5 based on attributes of education, occupation, per capita income, housing condition and consumer durables and other family assets.

RESULTS

Social classes 1, 2 and 3 were mainly high and middle socioeconomic groups and 3 and 4 low income groups. The prevalence of CAD and coronary risk factors hypercholesterolemia, hypertension, diabetes mellitus and sedentary lifestyle were significantly higher among social classes 1, 2 and 3 in both sexes compared to lower social classes. Mean serum cholesterol, triglycerides, low density lipoprotein cholesterol and blood pressure were significantly associated with higher and middle social classes. Smoking was significantly associated with lower social classes. Multivariate logistic regression analysis after adjustment of age revealed that social class was positively associated with CAD (odds ratio: men 0.84, women 0.86), hypercholesterolemia (men 0.87, women 0.85), hypertension (men 0.91, women 0.89), diabetes mellitus (men 0.71, women 0.68) and sedentary lifestyle (men 0.68, women 0.66). Smoking was significantly associated with CAD in men.

CONCLUSION

Social class 1, 2 and 3 in an urban population of India have a higher prevalence of CAD and coronary risk factors hypercholesterolemia, hypertension, diabetes mellitus and sedentary lifestyle in both sexes.

摘要

目的

确定社会阶层与冠心病危险因素及冠状动脉疾病(CAD)患病率之间的关联。

设计与背景

对莫拉达巴德市20条随机选取街道进行的全社区横断面调查。

研究对象与方法

随机选取1806名年龄在25 - 64岁的城市居民(904名男性和902名女性)。调查方法包括医生和营养师发放问卷、体格检查及心电图检查。所有研究对象根据教育程度、职业、人均收入、住房条件、耐用消费品及其他家庭资产等属性分为1 - 5个社会阶层。

结果

社会阶层1、2和3主要为高社会经济和中等社会经济群体,阶层3和4为低收入群体。与较低社会阶层相比,社会阶层1、2和3中男女CAD及冠心病危险因素(高胆固醇血症、高血压糖尿病和久坐生活方式)的患病率显著更高。平均血清胆固醇、甘油三酯、低密度脂蛋白胆固醇和血压与较高和中等社会阶层显著相关。吸烟与较低社会阶层显著相关。年龄调整后的多因素逻辑回归分析显示,社会阶层与CAD(比值比:男性0.84,女性0.86)、高胆固醇血症(男性0.87,女性0.85)、高血压(男性0.91,女性0.89)、糖尿病(男性0.71,女性0.68)和久坐生活方式(男性0.68,女性0.66)呈正相关。吸烟与男性CAD显著相关。

结论

在印度城市人口中,社会阶层1、2和3中男女CAD及冠心病危险因素(高胆固醇血症、高血压、糖尿病和久坐生活方式)的患病率更高。

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