Lewis D D, Shelton G D, Piras A, Dee J F, Robins G M, Herron A J, Fries C, Ginn P E, Hulse D A, Simpson D L, Allen D A
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610, USA.
J Am Anim Hosp Assoc. 1997 Mar-Apr;33(2):177-88. doi: 10.5326/15473317-33-2-177.
The clinical findings in 18 dogs with gracilis (n = 17) or semitendinosus (n = 1) myopathy are described. Each dog had a similar hind-limb gait abnormality characterized by a shortened stride with a rapid, elastic medial rotation of the paw, internal rotation of the hock and external rotation of the calcaneus [corrected] and internal rotation of the stifle during the mid-to-late swing phase of the stride. Medical management prior to or in lieu of surgery was attempted (n = 8) with no apparent response. Fifteen dogs had one or multiple surgical procedures. Although transection, partial excision, or complete resection of the affected muscle resulted in resolution of lameness following surgery, lameness recurred six weeks to five months (mean, 2.5 months; median, two months) following surgery. Adjunctive medical treatment did not prevent recurrence. Variable replacement of the affected muscle with fibrous connective tissue (predominantly along the caudolateral border of the muscle) was evident grossly, and replacement of myofibers with fibrous connective tissue was confirmed histologically. A definitive etiology could not be established.
本文描述了18只患有股薄肌（n = 17）或半腱肌（n = 1）肌病犬的临床症状。每只犬均有类似的后肢步态异常，其特征为步幅缩短，在步幅的中晚期摆动阶段，爪子快速、弹性地向内旋转，跗关节内旋，跟骨外旋[已修正]，膝关节内旋。8只犬尝试了手术前或替代手术的药物治疗，但无明显效果。15只犬接受了一次或多次手术。虽然对受影响肌肉进行横断、部分切除或完全切除可使术后跛行症状消失，但跛行在术后6周至5个月（平均2.5个月；中位数2个月）复发。辅助药物治疗不能预防复发。大体观察可见受影响肌肉被纤维结缔组织不同程度替代（主要沿肌肉后外侧边缘），组织学检查证实肌纤维被纤维结缔组织替代。病因尚不明确。
