Chattopadhyay A, Roberts T M, Jervis R E
Arch Environ Health. 1977 Sep-Oct;32(5):226-36. doi: 10.1080/00039896.1977.10667286.
Lead was measured by photon activation analysis in scalp hair from three population groups with varied types of environmental exposure. Concentrations of lead in hair increased from rural to urban to smelter areas with medians of 9.1, 15.3, and 48.5 ppm, respectively. Boys under 16 residing near smelters showed consistently higher lead levels than girls of the same age group and from the same area. A history of exposure to lead was deduced from the distribution of concentration along the hair length by analyzing 1-or 2-cm segments of hair strands. A reasonably good blood lead-hair lead correlation was obtained for individuals who appeared to be in a steady state with respect to intake and excretion of lead. The analytical method for the photonuclear determination of lead in hair, the hair washing procedure, and the advantages of using hair as an epidemiologic monitor are described.
通过光子活化分析测定了来自三种不同环境暴露类型人群组的头皮头发中的铅含量。头发中铅的浓度从农村地区到城市地区再到冶炼厂地区逐渐升高，中位数分别为9.1 ppm、15.3 ppm和48.5 ppm。居住在冶炼厂附近的16岁以下男孩的铅含量始终高于同年龄组且来自同一地区的女孩。通过分析1或2厘米长的发束片段，根据沿头发长度的浓度分布推断铅暴露史。对于铅摄入和排泄似乎处于稳定状态的个体，获得了血铅与发铅之间相当良好的相关性。描述了头发中铅的光核测定分析方法、头发清洗程序以及使用头发作为流行病学监测指标的优势。
