Wespes E, Sattar A A, Golzarian J, Wery D, Daoud N, Schulman C C
Department of Urology, Erasme Hospital, Brussels, Belgium.
J Urol. 1997 May;157(5):1678-80. doi: 10.1016/s0022-5347(01)64833-x.
We investigated whether a relationship exists between the flow to maintain an erection obtained at cavernosometry and the alteration of intracavernous structures in impotent patients with corporeal veno-occlusive dysfunction and normal arterial inflow.
Computerized histomorphometric analysis of smooth muscle and elastic fibers, and endothelial cells was compared to the flow necessary to maintain erection after intracavernous vasoactive drug injection in 18 patients with corporeal veno-occlusive dysfunction.
A significant correlation between percentage of smooth muscle fibers and flow to maintain erection was observed, while no correlation was noted with elastic fibers and endothelial cells.
Corporeal veno-occlusive dysfunction seems to be due mainly to smooth muscular alterations. According to this observation treatment of impotent patients with this abnormality should not be restricted to the penile veins but should also include the intracavernous structures, predominantly the muscular component.
我们研究了在海绵体测压时获得的维持勃起的血流量与患有海绵体静脉闭塞功能障碍且动脉流入正常的阳痿患者海绵体内结构改变之间是否存在关联。
对18例海绵体静脉闭塞功能障碍患者的平滑肌、弹性纤维和内皮细胞进行计算机组织形态计量分析，并与海绵体内注射血管活性药物后维持勃起所需的血流量进行比较。
观察到平滑肌纤维百分比与维持勃起的血流量之间存在显著相关性，而与弹性纤维和内皮细胞无相关性。
海绵体静脉闭塞功能障碍似乎主要是由于平滑肌改变所致。根据这一观察结果，对患有这种异常的阳痿患者的治疗不应仅限于阴茎静脉，还应包括海绵体内结构，主要是肌肉成分。
