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具有潜在生物活性的新型(4-烷基氨基-4'-氟)-二苯砜的合成

Synthesis of new (4-alkylamino-4'-fluoro)-diphenyl sulphones with potential biological activity.

作者信息

de Sousa Júnior P T, Miller J, Giesbrecht A M

机构信息

Instituto de Química, USP, São Paulo, SP, Brasil.

出版信息

An Acad Bras Cienc. 1996;68(2):161-4.

PMID:9113300
Abstract

In the present work, we report the synthesis and characterization of five (4-alkylalmino-4'-fluoro)-diphenyl sulphones, four of which have not been described before. In a preliminary evaluation of their biological activity, these products showed no effect on several Gram-positive and Gram-negative bacteria and yeasts.

摘要

在本研究中,我们报告了五种(4-烷基氨基-4'-氟)二苯砜的合成与表征,其中四种此前未见报道。在对其生物活性的初步评估中,这些产物对几种革兰氏阳性菌、革兰氏阴性菌及酵母菌均无作用。

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