抗菌和抗真菌剂的研究。十二——某些二芳基吡咯曼尼希碱的合成及抗菌活性
Research on antibacterial and antifungal agents. XII--Synthesis and antimicrobial activity of some Mannich bases of diarylpyrroles.
作者信息
Porretta G C, Biava M, Fioravanti R, Fischetti M, Boccia R, Villa A, Simonetti N
机构信息
Dipartimento di Studi di Chimica e Tecnologia delle Sostanze Biologicamente Attive, Università La Sapienza di Roma, Italy.
出版信息
Farmaco. 1995 Sep;50(9):617-23.
PMID:7495473
Abstract
The synthesis and antimicrobial activity of some Mannich bases of diarylpyrroles are reported. The obtained data show that activity is closely connected to molecular basicity. Results are discussed on the basis of structure activity relationships.
摘要
报道了一些二芳基吡咯曼尼希碱的合成及其抗菌活性。所得数据表明，活性与分子碱性密切相关。根据构效关系对结果进行了讨论。
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