Yamamoto K, Ikeda U, Minezaki K K, Fukazawa H, Mizuno O, Kim S, Fujikawa H, Sekiguchi H, Shimada K
Department of Cardiology, Jichi Medical School, Tochigi, Japan.
Am J Cardiol. 1997 Apr 15;79(8):1131-5. doi: 10.1016/s0002-9149(97)00064-7.
We investigated the plasma levels of molecular markers for the status of thrombin generation and fibrinolysis in patients with mitral stenosis before and after percutaneous mitral valvuloplasty. Our results show that percutaneous mitral valvuloplasty results in decreased coagulation activity, suggesting that percutaneous mitral valvuloplasty is also useful for prevention of systemic embolism in patients with mitral stenosis.
我们研究了经皮二尖瓣球囊成形术前后二尖瓣狭窄患者凝血酶生成和纤维蛋白溶解状态的分子标志物血浆水平。我们的结果表明,经皮二尖瓣球囊成形术可降低凝血活性,提示经皮二尖瓣球囊成形术对预防二尖瓣狭窄患者的全身性栓塞也有效。