Fenster L, Hubbard A E, Windham G C, Waller K O, Swan S H
Department of Health Services, Reproductive Epidemiology Section, Berkeley, CA 94704, USA.
Epidemiology. 1997 Jan;8(1):66-74. doi: 10.1097/00001648-199701000-00011.
We examined the relation of physical exertion to spontaneous abortion in a prospective study of 5,144 pregnant women. In a first trimester interview, we obtained data on employment and physical activity at work and at home, as well as other potential risk factors for spontaneous abortion. We measured exertion as follows: time spent working, standing and bending at work, hours between breaks, and hours spent doing housework or yardwork; shift worked; number of times lifted weights and more than 15 pounds at work or at home; number of children under age 5 years cared for at home. None of the exertion measures was appreciably associated with an increased risk of spontaneous abortion overall. In addition, physical activity at work and at home combined was not related to increased risk. For women with a history of two or more spontaneous abortions, standing at work more than 7 hours per day was associated with an adjusted odds ratio (OR) of 4.3 [95% confidence limits (CL) = 1.6, 11.7], whereas standing at work for 7 hours or less was associated with an adjusted OR of 1.7 (95% CL = 1.1, 2.6). Women without such a history who stood more than 7 hours at work had an adjusted OR near unity.
我们在一项对5144名孕妇的前瞻性研究中，考察了体力活动与自然流产之间的关系。在孕早期的一次访谈中，我们获取了有关工作及家中的就业情况、体力活动，以及其他自然流产潜在风险因素的数据。我们按以下方式衡量体力活动：工作时长、工作时站立和弯腰的时间、休息间隔时长、做家务或庭院劳作的时长；轮班情况；在工作或家中提起重物且重量超过15磅的次数；在家中照顾的5岁以下儿童数量。总体而言，没有任何一项体力活动指标与自然流产风险增加有明显关联。此外，工作和家中的体力活动综合起来也与风险增加无关。对于有两次或更多次自然流产史的女性，每天工作时站立超过7小时，经调整后的优势比（OR）为4.3 [95%置信区间（CL）= 1.6, 11.7]，而每天工作时站立7小时及以下，经调整后的OR为1.7（95% CL = 1.1, 2.6）。没有此类病史且工作时站立超过7小时的女性，经调整后的OR接近1。
