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节段性硬膜外镇痛后的胎儿心率模式与子宫活动

Fetal heart rate patterns and uterine activity after segmental epidural analgesia.

作者信息

Jouppila P, Jouppila R, Käär K, Merilä M

出版信息

Br J Obstet Gynaecol. 1977 Jul;84(7):481-6. doi: 10.1111/j.1471-0528.1977.tb12629.x.

DOI:10.1111/j.1471-0528.1977.tb12629.x
PMID:911702
Abstract

The effects of low-dose segmental epidural analgesia on fetal heart rate (FHR) patterns, uterine activity, and some clinical features were examined in a series of 105 normal parturients. The aim of the analgesic technique was to relieve pain during the first stage of labour by blocking the sensory nerve fibres at the spinal level of T 10 to T12, with either 0-5 per cent bupivacaine or bupivacaine with adrenaline 1 : 200 000, the dose varying from 10 to 25 mg. Obvious pathological changes (late decelerations, prolonged fetal bradycardia, variable deceleration, or loss of beat to beat variation) in FHR patterns within the first 30 minutes after the beginning of analgesia were noted in 9 per cent of the patients. Addition of adrenaline to the analgesic agent seemed to reduce uterine activity for 60 minutes after the analgesia and this was reflected in a longer interval between the block and delivery. A 25 per cent fall in systolic blood pressure was recorded in 11 per cent of the patients. Nine patients required vacuum extractions. Our results show that the epidural technique employed has distinct advantages over the previous methods, which require larger doses of the analgesic, agent, and is therefore safer for the fetus; the addition of adrenaline to the analgesic agent is contraindicated.

摘要

在105例正常产妇中,研究了低剂量节段性硬膜外镇痛对胎儿心率(FHR)模式、子宫活动及一些临床特征的影响。该镇痛技术的目的是通过在T10至T12脊髓水平阻断感觉神经纤维,使用0.5%布比卡因或含1:200 000肾上腺素的布比卡因,剂量为10至25mg,以减轻第一产程的疼痛。9%的患者在镇痛开始后的前30分钟内,FHR模式出现明显的病理变化(晚期减速、持续性胎儿心动过缓、变异减速或逐搏变异消失)。在镇痛剂中添加肾上腺素似乎会在镇痛后60分钟内降低子宫活动,这反映在阻滞与分娩之间的间隔时间更长。11%的患者收缩压下降了25%。9例患者需要进行真空吸引助产。我们的结果表明,所采用的硬膜外技术比以前需要更大剂量镇痛剂的方法具有明显优势,因此对胎儿更安全;镇痛剂中添加肾上腺素是禁忌的。

相似文献

1
Fetal heart rate patterns and uterine activity after segmental epidural analgesia.节段性硬膜外镇痛后的胎儿心率模式与子宫活动
Br J Obstet Gynaecol. 1977 Jul;84(7):481-6. doi: 10.1111/j.1471-0528.1977.tb12629.x.
2
Epidural analgesia in labour. IV. Influence on uterine activity and fetal heart rate.分娩时的硬膜外镇痛。IV. 对子宫活动和胎儿心率的影响。
Acta Obstet Gynecol Scand. 1976;55(4):305-10. doi: 10.3109/00016347609158502.
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Maternal and fetal effects of adrenaline with bupivacaine (0.25%) for epidural analgesia during labour.肾上腺素与布比卡因(0.25%)用于分娩期间硬膜外镇痛的母胎效应。
Eur J Anaesthesiol. 1996 Nov;13(6):594-8. doi: 10.1046/j.1365-2346.1996.00053.x.
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Cardiovascular effects of extradural analgesia in labour: comparison of bupivacaine with lignocaine.
Br J Anaesth. 1975 Dec;47(12):1297-1303. doi: 10.1093/bja/47.12.1297.
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Safety and efficacy of epinephrine added to bupivacaine for lumbar epidural analgesia in obstetrics.
Anesth Analg. 1985 Jun;64(6):585-91.
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Cardiovascular changes in labour associated with extradural analgesia using bupivacaine.使用布比卡因进行硬膜外镇痛时分娩过程中的心血管变化。
Br J Anaesth. 1975 Dec;47(12):1291-5. doi: 10.1093/bja/47.12.1291.
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The effects of epidural anesthesia on electronic fetal heart rate monitoring.
Clin Perinatol. 1982 Feb;9(1):55-62.
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Selective lumbar epidural block in labour. A clinical analysis.分娩时选择性腰段硬膜外阻滞。临床分析。
Acta Anaesthesiol Scand. 1977;21(3):174-81. doi: 10.1111/j.1399-6576.1977.tb01207.x.
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[Cardiotocographic changes in epidural analgesia with bupivacaine].[布比卡因硬膜外镇痛时的胎心监护变化]
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