来自禽蛋蛋清的蛋白酶抑制剂。
Protein proteinase inhibitors from avian egg whites.
作者信息
Saxena I, Tayyab S
机构信息
Department of Biochemistry, Faculty of Medicine, Aligarh Muslim University, India.
出版信息
Cell Mol Life Sci. 1997 Jan;53(1):13-23. doi: 10.1007/pl00000575.
Abstract
Avian egg whites are a rich source of protein inhibitors of proteinases belonging to all four mechanistic classes. Ovomucoid and ovoinhibitor are multidomain Kazal-type inhibitors with each domain containing an actual or putative reactive site for a serine proteinase. Cystatin is a cysteine proteinase inhibitor, while ovostatin inhibits proteinases of all four mechanistic classes. In this review we have summarized the general features, isolation, inhibitory mechanism and evolutionary aspects of these inhibitors.
摘要
禽蛋清是属于所有四种机制类别的蛋白酶的蛋白质抑制剂的丰富来源。卵类黏蛋白和卵抑制剂是多结构域的卡扎尔型抑制剂，每个结构域都含有一个针对丝氨酸蛋白酶的实际或推定的活性位点。胱抑素是一种半胱氨酸蛋白酶抑制剂，而卵抑素则抑制所有四种机制类别的蛋白酶。在这篇综述中，我们总结了这些抑制剂的一般特征、分离方法、抑制机制和进化方面。
相似文献
1
Protein proteinase inhibitors from avian egg whites.来自禽蛋蛋清的蛋白酶抑制剂。
Cell Mol Life Sci. 1997 Jan;53(1):13-23. doi: 10.1007/pl00000575.
2
Ovomucoid and ovoinhibitor isolated from chicken egg white are immunologically cross-reactive.从鸡蛋白中分离出的类卵黏蛋白和卵类黏蛋白抑制剂具有免疫交叉反应性。
Biochem Biophys Res Commun. 1983 Jan 14;110(1):75-81. doi: 10.1016/0006-291x(83)91262-7.
3
Ovostatin: a proteinase inhibitor in egg whites that is homologous to alpha 2-macroglobulin.卵抑素：蛋清中的一种蛋白酶抑制剂，与α2-巨球蛋白同源。
Prog Clin Biol Res. 1985;180:283-5.
4
Egg white proteins.
Comp Biochem Physiol B. 1991;100(1):1-9. doi: 10.1016/0305-0491(91)90076-p.
5
A proteinase inhibitor from egg yolk of hen is an ovoinhibitor analog.来自母鸡蛋黄的一种蛋白酶抑制剂是一种卵类粘蛋白类似物。
Biochim Biophys Acta. 1996 Jun 7;1295(1):96-102. doi: 10.1016/0167-4838(96)00034-9.
6
Ovoinhibitor introns specify functional domains as in the related and linked ovomucoid gene.卵类粘蛋白抑制剂内含子如在相关且相连的卵类粘蛋白基因中一样，确定功能域。
J Biol Chem. 1987 Apr 25;262(12):5899-907.
7
8
9
Ovomucoid third domains from 100 avian species: isolation, sequences, and hypervariability of enzyme-inhibitor contact residues.来自100种鸟类的类卵黏蛋白第三结构域：酶-抑制剂接触残基的分离、序列及高变异性
Biochemistry. 1987 Jan 13;26(1):202-21. doi: 10.1021/bi00375a028.
10
Kininogens: inhibitors of cysteine proteinases in plasma and a similar inhibitor in chicken egg white.
Biomed Biochim Acta. 1986;45(11-12):1385-90.
引用本文的文献
1
Bacterial Degradation of Antinutrients in Foods: The Genomic Insight.食品中抗营养因子的细菌降解：基因组学见解
Foods. 2024 Jul 29;13(15):2408. doi: 10.3390/foods13152408.
2
Advances in Understanding the Antioxidant and Antigenic Properties of Egg-Derived Peptides.了解鸡蛋衍生肽的抗氧化和抗原性特性的进展。
Molecules. 2024 Mar 16;29(6):1327. doi: 10.3390/molecules29061327.
3
Ovotransferrin Supplementation Improves the Iron Absorption: An In Vitro Gastro-Intestinal Model.卵转铁蛋白补充剂可改善铁吸收：一种体外胃肠道模型
Biomedicines. 2021 Oct 26;9(11):1543. doi: 10.3390/biomedicines9111543.
4
Love bites: male frogs (Plectrohyla, Hylidae) use teeth scratching to deliver sodefrin precursor-like factors to females during amplexus.爱的印记：雄性蛙类（雨蛙科的褶雨蛙属）在抱对时利用牙齿刮擦向雌性传递类速激肽释放因子前体。
Front Zool. 2021 Nov 25;18(1):59. doi: 10.1186/s12983-021-00445-6.
5
Protease Inhibitors Protect Bovine Colostrum or Chicken Egg Growth Factors from Pancreatic Enzyme Digestion in AGS Cells or Colitic Rats.蛋白酶抑制剂可保护牛初乳或鸡卵生长因子免受胰腺酶在 AGS 细胞或结肠炎大鼠中的消化。
J Nutr. 2021 Oct 1;151(10):3036-3044. doi: 10.1093/jn/nxab197.
6
Three-dimensional structures of avian beta-microseminoproteins: insight from the chicken egg-specific beta-microseminoprotein 3 paralog.禽类β-微精氨酸蛋白的三维结构：鸡卵特异性β-微精氨酸蛋白 3 同源物的启示。
FEBS Open Bio. 2021 Jun;11(6):1739-1756. doi: 10.1002/2211-5463.13166. Epub 2021 May 24.
7
A Novel, Orally Delivered Antibody Therapy and Its Potential to Prevent Infection in Pre-clinical Models.一种新型口服抗体疗法及其在临床前模型中预防感染的潜力。
Front Microbiol. 2020 Sep 22;11:578903. doi: 10.3389/fmicb.2020.578903. eCollection 2020.
8
The seminal acrosin-inhibitor ClTI1/SPINK2 is a fertility-associated marker in the chicken.顶体蛋白酶抑制剂 ClTI1/SPINK2 是鸡中与生育能力相关的标志物。
Mol Reprod Dev. 2019 Jul;86(7):762-775. doi: 10.1002/mrd.23153. Epub 2019 Apr 29.
9
Duck egg albumen: physicochemical and functional properties as affected by storage and processing.鸭蛋蛋清：受储存和加工影响的理化性质及功能特性
J Food Sci Technol. 2019 Mar;56(3):1104-1115. doi: 10.1007/s13197-019-03669-x. Epub 2019 Feb 28.
10
The Golden Egg: Nutritional Value, Bioactivities, and Emerging Benefits for Human Health.金蛋：营养价值、生物活性及对人类健康的新益处。
Nutrients. 2019 Mar 22;11(3):684. doi: 10.3390/nu11030684.
Zotero 插件