Rumbak M J, Graves A E, Scott M P, Sporn G K, Walsh F W, Anderson W M, Goldman A L
Department of Internal Medicine, University of South Florida College of Medicine, Tampa General Hospital, USA.
Crit Care Med. 1997 Mar;25(3):413-7. doi: 10.1097/00003246-199703000-00007.
This study was undertaken to test the hypothesis that a tracheal tube occlusion protocol predicts clinically important obstruction to air flow in patients requiring prolonged mechanical ventilation, making routine bronchoscopy unnecessary.
A prospective evaluation of 75 patients who were clinically ready to be decannulated. All patients underwent the tracheal tube occlusion protocol followed by bronchoscopy.
Three hospitals affiliated with a college of medicine.
Over a 24-month period, 52 males and 23 females were enrolled in the study. Mean age was 55 yrs (range 25 to 85). Mean endotracheal/tracheostomy time was 2.4/8.9 wks (range 1 to 4/5 to 14). All patients were mechanically ventilated for at least 4 wks and were successfully weaned from the mechanical ventilator for at least 48 hrs. During spontaneous breathing, these data were observed: minute ventilation of < 10 L/min; resting respiratory rate of < 18 breaths/min; and arterial oxygen saturation of > 90% on 40% oxygen tracheal collar mask. The tracheal tube occlusion protocol consisted of deflating the cuff on the fenestrated tracheal tube and occluding the tube.
Patients who developed respiratory distress when the tracheal tube was occluded were deemed to have failed the protocol. At bronchoscopy, the patients were asked to cough and hyperventilate in an attempt to forcibly reduce the cross-sectional area of the trachea. A sustained, subjectively assessed decrease of > or = 50% of the effective cross-sectional area of the trachea was considered to be an indication for intervention.
Sixty-three (84%) of 75 patients tolerated the tracheal tube occlusion protocol. Twelve (16%) of 75 patients developed signs of respiratory distress and showed decreased oxygen saturation values necessitating uncapping of the tracheal tube. All patients had some degree of tracheal injury. However, those patients who failed to tolerate the tracheal tube occlusion protocol had clinically important tracheal obstruction to air flow.
A tracheal tube occlusion protocol can predict clinically important obstruction to air flow after prolonged mechanical ventilation.
本研究旨在验证如下假设,即气管插管封堵方案能够预测需要长期机械通气的患者是否存在临床上重要的气流阻塞,从而无需进行常规支气管镜检查。
对75例临床已准备好拔管的患者进行前瞻性评估。所有患者均接受气管插管封堵方案,随后进行支气管镜检查。
一所医学院附属的三家医院。
在24个月期间,52例男性和23例女性纳入本研究。平均年龄55岁(范围25至85岁)。平均气管内/气管造口插管时间为2.4/8.9周(范围1至4/5至14周)。所有患者均接受机械通气至少4周,并成功脱机至少48小时。在自主呼吸期间,观察到以下数据:分钟通气量<10 L/分钟;静息呼吸频率<18次/分钟;在使用40%氧气气管颈罩面罩时动脉血氧饱和度>90%。气管插管封堵方案包括放气带孔气管插管上的套囊并封堵插管。
气管插管封堵时出现呼吸窘迫的患者被视为封堵方案失败。在支气管镜检查时,要求患者咳嗽并过度通气,试图强行减小气管的横截面积。气管有效横截面积持续、主观评估减少≥50%被视为干预指征。
75例患者中有63例(84%)耐受气管插管封堵方案。75例患者中有12例(16%)出现呼吸窘迫体征,血氧饱和度值下降,需要松开气管插管。所有患者均有一定程度的气管损伤。然而,那些不能耐受气管插管封堵方案的患者存在临床上重要的气管气流阻塞。
气管插管封堵方案能够预测长期机械通气后临床上重要的气流阻塞。