Boqué M C, Gualis B, Sandiumenge A, Rello J
University Hospital Joan XXIII, University Rovira i Virgili, Mallafré Guasch 4, 43007 Tarragona, Spain.
Intensive Care Med. 2004 Dec;30(12):2204-9. doi: 10.1007/s00134-004-2465-4. Epub 2004 Oct 2.
To quantify the incidence and degree of endotracheal tube intraluminal obstruction after mechanical ventilation and its relation to time of intubation.
Prospective observational study.
A 14-bed medical-surgical intensive care unit at a university-affiliated teaching hospital.
Ninety-four endotracheal tubes used in 80 patients requiring mechanical ventilation for more than 12 h.
Acoustic reflectometry was performed in every endotracheal tube after patient extubation to measure its volume reduction. The intraluminal volumes of used endotracheal tubes in mechanically ventilated patients were significantly lower than those of unused tubes of the same size (5.52+/-0.92 ml(3) versus 6.54+/-0.79 ml(3), p<0.05). The mean difference in endotracheal tube segment volumes was 15.2% (range 0-66%). Volume reduction was above 10% in 60.8% of the tubes. In 22% of endotracheal tubes the remaining inner diameter was less than 7 mm. Reduction below this figure was less frequent (9.3%) in tubes 8 mm or more (p<0.05). The percentage of endotracheal tube volume reduction was not associated with the duration of intubation (r=-0.09, p= n.s.) Peak pressure measured before extubation did not predict obstruction (r=0.11, p= n.s.).
Inadvertent endotracheal tube obstruction was common in patients requiring mechanical ventilation and may be significant as early as at 24 h. Moderate obstruction in endotracheal tube lumens should be suspected in cases of difficulties in weaning, even in patients who were ventilated for less than 1 day.
量化机械通气后气管内导管管腔内阻塞的发生率和程度及其与插管时间的关系。
前瞻性观察研究。
一所大学附属医院的拥有14张床位的内科-外科重症监护病房。
80例需要机械通气超过12小时的患者使用的94根气管内导管。
在患者拔管后对每根气管内导管进行声反射测量以测量其容积减少情况。机械通气患者使用的气管内导管的管腔容积显著低于相同尺寸的未使用导管(5.52±0.92 ml³ 对 6.54±0.79 ml³,p<0.05)。气管内导管节段容积的平均差异为15.2%(范围0-66%)。60.8%的导管容积减少超过10%。22%的气管内导管剩余内径小于7 mm。在8 mm及以上的导管中,低于此数值的减少情况较少见(9.3%)(p<0.05)。气管内导管容积减少的百分比与插管持续时间无关(r=-0.09,p=无统计学意义)。拔管前测量的峰值压力不能预测阻塞情况(r=0.11,p=无统计学意义)。
需要机械通气的患者中意外的气管内导管阻塞很常见,并且可能早在24小时就很明显。即使在通气时间少于1天的患者中,在撤机困难的情况下也应怀疑气管内导管管腔存在中度阻塞。