Mielck A, Reitmeir P, Wjst M
Institut fur Medizinische Informatik und Systemforschung (MEDIS), GSF-Forschungszentrum fur Umwelt und Gesundheit, Neuherherg, Germany.
Int J Epidemiol. 1996 Apr;25(2):388-93. doi: 10.1093/ije/25.2.388.
A review of studies on the association between childhood asthma and socioeconomic status (SES) in industrialized countries leads to the conclusion that there does not seem to be a clear association. A study from Aberdeen published 25 years ago, however, shows that among children with asthma, severe asthma is most prevalent in the lower social class, but this distinction between grades of asthma severity has been largely ignored since.
We screened all fourth grade schoolchildren of German nationality in Munich (4434 children, response rate 87 percent), distinguishing three severity grades in the same way as the study in Aberdeen.
Prevalences of childhood asthma are reported by severity grade and SES. Prevalence of severe asthma was found to be significantly higher in the low as compared with the high socioeconomic group (Odds ratio = 2.37; 95 percent confidence interval: 1.28-4.41). This association could not be explained by established risk factors.
More attention should be paid to the association between severe asthma and SES, with measures such as targeting early diagnosis and treatment towards low socioeconomic groups.
对工业化国家中儿童哮喘与社会经济地位(SES)之间关联的研究综述得出的结论是,两者之间似乎没有明确的关联。然而,25年前阿伯丁发表的一项研究表明,在患有哮喘的儿童中,重度哮喘在社会阶层较低的人群中最为普遍,但此后哮喘严重程度等级之间的这种差异在很大程度上被忽视了。
我们对慕尼黑所有四年级的德国籍学童进行了筛查(4434名儿童,应答率87%),采用与阿伯丁研究相同的方式区分三个严重程度等级。
按严重程度等级和社会经济地位报告了儿童哮喘的患病率。发现低社会经济群体中重度哮喘的患病率显著高于高社会经济群体(优势比 = 2.37;95%置信区间:1.28 - 4.41)。这种关联无法用既定的风险因素来解释。
应更多关注重度哮喘与社会经济地位之间的关联,采取诸如针对低社会经济群体进行早期诊断和治疗等措施。