McDaniel D, Besada E
J Am Optom Assoc. 1996 Feb;67(2):109-14.
Recent studies have shown an association between hypothyroidism and primary open-angle glaucoma (POAG). When hypothyroidism occurs, accumulation of hyaluronic acid within the trabecular meshwork may cause an increase in outflow resistance and intraocular pressure (IOP). This increase may be reversible with use of systemic treatment.
A hypothyroid patient is described whose IOP inversely varied with the use or the discontinuation of systemic hypothyroid medications.
The patient's IOP was controlled when she complied with systemic treatment.
In some cases, hypothyroidism may contribute to the genesis of open-angle glaucoma. Systemic treatment alone may be adequate to prevent progression of a glaucomatous diseased state. It may be prudent to investigate the presence of undiagnosed hypothyroidism in individuals with poorly controlled POAG, in individuals with normal-tension glaucoma, and in newly diagnosed cases.
近期研究表明甲状腺功能减退与原发性开角型青光眼（POAG）之间存在关联。当发生甲状腺功能减退时，小梁网内透明质酸的积聚可能导致房水流出阻力增加和眼压（IOP）升高。这种升高通过全身治疗可能是可逆的。
描述了一名甲状腺功能减退患者，其眼压随全身甲状腺功能减退药物的使用或停用而呈反向变化。
患者在遵守全身治疗时眼压得到控制。
在某些情况下，甲状腺功能减退可能促成开角型青光眼的发生。仅全身治疗可能足以预防青光眼疾病状态的进展。对于原发性开角型青光眼控制不佳的个体、正常眼压性青光眼个体以及新诊断病例，调查是否存在未确诊的甲状腺功能减退可能是谨慎的做法。
