Smith K D, Tevaarwerk G J, Allen L H
Department of Ophthalmology, University of Western Ontario, London.
Can J Ophthalmol. 1992 Dec;27(7):341-4.
To examine the hypothesis that glaucoma may be a manifestation of unrecognized hypothyroidism, we studied 25 consecutive patients with newly diagnosed hypothyroidism who presented to an endocrinology clinic. Using tonography and tonometry, we demonstrated a reduction in facility of outflow in the hypothyroid state. With treatment of the hypothyroidism alone there was a statistically significant improvement in facility of outflow, intraocular pressure and Po/C (p < 0.002). Our results support the hypothesis that secondary open-angle glaucoma may be a manifestation of hypothyroidism and that the glaucoma will resolve on treatment of the primary disease.
为检验青光眼可能是未被识别的甲状腺功能减退症的一种表现这一假说，我们研究了连续25例新诊断为甲状腺功能减退症并就诊于内分泌科门诊的患者。通过眼压描记法和眼压测量法，我们证实在甲状腺功能减退状态下房水流畅系数降低。仅对甲状腺功能减退症进行治疗后，房水流畅系数、眼压和Po/C均有统计学意义的改善（p<0.002）。我们的结果支持以下假说：继发性开角型青光眼可能是甲状腺功能减退症的一种表现，且青光眼在原发性疾病得到治疗后会得到缓解。
