Goldberg D P, Gater R, Sartorius N, Ustun T B, Piccinelli M, Gureje O, Rutter C
Institute of Psychiatry, London.
Psychol Med. 1997 Jan;27(1):191-7. doi: 10.1017/s0033291796004242.
In recent years the 12-item General Health Questionnaire (GHQ-12) has been extensively used as a short screening instrument, producing results that are comparable to longer versions of the GHQ.
The validity of the GHQ-12 was compared with the GHQ-28 in a World Health organization study of psychological disorders in general health care. Results are presented for 5438 patients interviewed in 15 centres using the primary care version of the Composite International Diagnostic Instrument, or CIDI-PC.
Results were uniformly good, with the average area under the ROC curve 88, range from 83 to 95. Minor variations in the criteria used for defining a case made little difference to the validity of the GHQ, and complex scoring methods offered no advantages over simpler ones. The GHQ was translated into 10 other languages for the purposes of this study, and validity coefficients were almost as high as in the original language. There was no tendency for the GHQ to work less efficiently in developing countries. Finally gender, age and educational level are shown to have no significant effect on the validity of the GHQ.
If investigators wish to use a screening instrument as a case detector, the shorter GHQ is remarkably robust and works as well as the longer instrument. The latter should only be preferred if there is an interest in the scaled scores provided in addition to the total score.
近年来,12项一般健康问卷(GHQ - 12)作为一种简短的筛查工具被广泛使用,其产生的结果与更长版本的GHQ相当。
在世界卫生组织关于普通医疗保健中心理障碍的一项研究中,对GHQ - 12与GHQ - 28的有效性进行了比较。使用综合国际诊断工具初级保健版(CIDI - PC),展示了在15个中心对5438名患者进行访谈的结果。
结果一致良好,ROC曲线下的平均面积为88,范围从83到95。用于定义病例的标准的微小变化对GHQ的有效性影响不大,复杂的评分方法并不比简单方法更具优势。为了本研究,GHQ被翻译成其他10种语言,有效性系数几乎与原文一样高。在发展中国家,GHQ没有表现出效率较低的趋势。最后,性别、年龄和教育水平对GHQ的有效性没有显著影响。
如果研究者希望使用一种筛查工具来检测病例,较短的GHQ非常可靠,其效果与较长的工具一样好。只有当除总分外还对量表分数感兴趣时,才应选择较长的工具。