Endsley Paige, Weobong Benedict, Nadkarni Abhijit
Columbia University, Mailman School of Public Health, United States.
Sangath, 841/1, Alto Porvorim, Bardez, B/H Electricty Dept, H No 451 (168), Bhatkar Waddo, Socorro, Bardez, Porvorim, Goa 403521, India; London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
Asian J Psychiatr. 2017 Aug;28:106-110. doi: 10.1016/j.ajp.2017.03.023. Epub 2017 Mar 24.
There have not been many attempts to validate screening measures for common mental disorders (CMD) in low- and middle-income countries. The aim of this study was to examine the criterion validity of the General Health Questionnaire 12 (GHQ-12) in a community-based study from Goa, India.
Concurrent and convergent validity of the GHQ-12 were assessed against the Mini International Neuropsychiatric Interview (MINI) and World Health Organization Disability Assessment Scale (WHODAS) for CMD and functional status through the secondary analysis of a community cohort of men from Goa, India. Criterion validity of the GHQ-12 was determined using ROC analyses with the MINI case criterion as the gold standard. Concurrent validity was assessed against the gold standard of WHODAS functional disability and number of disability days.
In a sample of men (n=773), the GHQ-12 showed high internal reliability (Cronbach's alpha of 0.82) and acceptable criterion validity (Area under the receiver operating characteristic curve being 0.71). It had adequate psychometric properties for the detection of CMD (sensitivity of 68.75%; specificity of 73.14%) with the optimal cut-off score for identification of CMD being 2.
In order to optimize the usefulness and validity of the GHQ-12, a low cut-off point for CMD may be beneficial in Goa, India. Further validation studies for the GHQ-12 should be conducted for continued validation of the test for use in the community.
在低收入和中等收入国家,对常见精神障碍(CMD)筛查措施进行验证的尝试并不多。本研究旨在通过印度果阿邦一项基于社区的研究,检验一般健康问卷12项(GHQ - 12)的效标效度。
通过对印度果阿邦男性社区队列进行二次分析,以迷你国际神经精神访谈(MINI)和世界卫生组织残疾评估量表(WHODAS)为参照,评估GHQ - 12在CMD及功能状态方面的同时效度和聚合效度。以MINI病例标准作为金标准,采用ROC分析确定GHQ - 12的效标效度。以WHODAS功能残疾金标准和残疾天数评估同时效度。
在男性样本(n = 773)中,GHQ - 12显示出较高的内部信度(克朗巴哈系数为0.82)和可接受的效标效度(受试者工作特征曲线下面积为0.71)。它在检测CMD方面具有足够的心理测量学特性(灵敏度为68.75%;特异度为73.14%),识别CMD的最佳临界值为2。
为优化GHQ - 12的效用和效度,在印度果阿邦,较低的CMD临界值可能有益。应针对GHQ - 12开展进一步的验证研究,以便持续验证该测试在社区中的应用。