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对成人心脏内左向右分流的血氧测定评估的批判性重新评估。

A critical reappraisal of the oximetric assessment of intracardiac left-to-right shunting in adults.

作者信息

Pirwitz M J, Willard J E, Landau C, Hillis L D, Lange R A

机构信息

Department of Internal Medicine (Cardiovascular Division), the University of Texas Southwestern Medical Center, Dallas 75235-9047, USA.

出版信息

Am Heart J. 1997 Apr;133(4):413-7. doi: 10.1016/s0002-8703(97)70182-0.

DOI:10.1016/s0002-8703(97)70182-0
PMID:9124162
Abstract

Although the oximetric analysis of blood from the right heart chambers is the most commonly used method for assessing the presence of intracardiac left-to-right shunting, the data the analysis is based on are limited. In addition, uncertainty exists concerning the best way of estimating the mixed venous oxygen content in subjects with intraatrial left-to-right shunting. In 102 adults without left-to-right shunting, blood was obtained from the venae cavae and right heart chambers to measure oxygen content. The limits of normality of oxygen content differences were 0.5 ml/dl from venae cavae to right atrium, 0.6 ml/dl from right atrium to right ventricle, and 0.9 ml/dl from right ventricle to pulmonary artery. The pulmonary arterial oxygen content was best estimated by combining the superior and inferior vena caval oxygen contents according to the formula (2[SVC] + 3[IVC]) divided by 5, where SVC is the superior vena cava and IVC is the inferior venae cava. These data provide new oximetric criteria for establishing the presence of intracardiac left-to-right shunting in adults.

摘要

尽管对右心腔血液进行血氧分析是评估心内左向右分流是否存在的最常用方法,但该分析所依据的数据有限。此外,对于存在心房水平左向右分流的受试者,估算混合静脉血氧含量的最佳方法仍存在不确定性。在102名无左向右分流的成年人中,从腔静脉和右心腔采集血液以测量血氧含量。腔静脉至右心房血氧含量差值的正常范围为0.5 ml/dl,右心房至右心室为0.6 ml/dl,右心室至肺动脉为0.9 ml/dl。肺动脉血氧含量的最佳估算方法是根据公式(2[上腔静脉血氧含量] + 3[下腔静脉血氧含量])÷5来合并上、下腔静脉血氧含量,其中上腔静脉血氧含量用SVC表示,下腔静脉血氧含量用IVC表示。这些数据为判定成人是否存在心内左向右分流提供了新的血氧测定标准。

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