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梅克尔憩室:十年经验

Meckel's diverticulum: a ten-year experience.

作者信息

Arnold J F, Pellicane J V

机构信息

Department of Surgery, Carilion Roanoke Memorial Hospital, Virginia 24033, USA.

出版信息

Am Surg. 1997 Apr;63(4):354-5.

PMID:9124758
Abstract

Meckel's diverticulum (MD) is the most common congenital anomaly of the small intestine, occurring in up to 4 percent of the population. The majority of MD cases are discovered incidentally; however, they can occasionally cause serious bleeding or obstructive or inflammatory complications. We reviewed the charts of 58 patients with MD from 1984 to 1994 collecting data on age, sex, presentation, therapy, pathology, and surgical complications to try to identify factors suggestive of the need for surgical therapy and the associated morbidity and mortality of resection. There was a 1.3:1 male:female ratio, and although patients with MD were found at all ages, the majority were found in patients in the 4th and 5th decade of life. Forty-five of 58 were incidental, and 13 of 58 were symptomatic. The most common symptom was bowel obstruction (10 of 13). Forty-five of 58 MD cases were managed surgically, 71 percent by diverticulectomy and the remainder by segmental resection, with no associated morbidity or mortality. Symptomatic patients were more often male (77 vs 23%; P 0.06, Fisher's exact test), more often had ectopic mucosa (31 vs 16%; P, not significant), and were evenly distributed over all ages. These data suggest that, with the possible exception of male sex, there is no factor predictive of the development of symptoms in incidentally found MD. In light of this finding, the low operative morbidity and mortality, and the even age distribution in patients with complications of their MD, we recommend that MD be resected when found incidentally in the absence of an absolute contraindication.

摘要

梅克尔憩室(MD)是小肠最常见的先天性异常,发病率高达4%。大多数MD病例是偶然发现的;然而,它们偶尔也会引起严重出血、梗阻或炎症并发症。我们回顾了1984年至1994年58例MD患者的病历,收集了年龄、性别、临床表现、治疗、病理及手术并发症等数据,试图确定提示需要手术治疗的因素以及切除相关的发病率和死亡率。男女比例为1.3:1,尽管各年龄段均有MD患者,但大多数患者年龄在40至50岁之间。58例中有45例为偶然发现,58例中有13例有症状。最常见的症状是肠梗阻(13例中有10例)。58例MD病例中有45例接受了手术治疗,71%行憩室切除术,其余行节段性切除,无相关发病率或死亡率。有症状的患者男性更常见(77%对23%;P = 0.06,Fisher精确检验),异位黏膜更常见(31%对16%;P无显著性差异),且各年龄段分布均匀。这些数据表明,除男性外,偶然发现的MD中没有预测症状发生的因素。鉴于这一发现、手术低发病率和死亡率以及MD并发症患者年龄分布均匀,我们建议在无绝对禁忌证的情况下,偶然发现MD时应予以切除。

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