Derevianko I I, Kotliarova G A, Kondrat'eva E M, Khodyreva L A, Siniukhin V N
Antibiot Khimioter. 1996;41(12):30-3.
Two hundred and two isolates of gram-positive and gram-negative pathogens of urinary tract infection were tested for their susceptibility to cefpirome. In 64 to 97 per cent of the cases the susceptibility was high and exceeded that of other cephalosporins used in the treatment of urological patients. Cefpirome was used in the treatment of 26 patients with signs of urinary tract infection: 19 patients with pyelonephritis and 7 patients with prostatitis. The antibiotic was administered intravenously in a dose of 1 g twice a day for the treatment course of 5-7-10 days. The clinical and bacteriological efficacies amounted to 92 and 87 per cent respectively. The drug tolerance was good. The results demonstrated that cefpirome was useful in the empirical therapy of urinary tract infection.
对202株革兰氏阳性和革兰氏阴性尿路感染病原体进行了头孢匹罗敏感性测试。在64%至97%的病例中，敏感性较高，超过了用于治疗泌尿系统疾病患者的其他头孢菌素。头孢匹罗用于治疗26例有尿路感染迹象的患者：19例肾盂肾炎患者和7例前列腺炎患者。抗生素静脉注射，剂量为每日两次，每次1g，疗程为5 - 7 - 10天。临床和细菌学疗效分别为92%和87%。药物耐受性良好。结果表明，头孢匹罗在尿路感染的经验性治疗中是有用的。
