人尿中致病性大肠杆菌生长的营养需求。
Nutritional requirements for growth of uropathogenic Escherichia coli in human urine.
作者信息
Hull R A, Hull S I
机构信息
Department of Microbiology and Immunology, Baylor College of Medicine, Houston, Texas 77030, USA.
出版信息
Infect Immun. 1997 May;65(5):1960-1. doi: 10.1128/iai.65.5.1960-1961.1997.
Abstract
Enrichment with D-cycloserine was used to identify Escherichia coli auxotrophic mutants that exhibited limited growth in human urine. Bacterial synthesis of guanine, arginine, and glutamine was found to be required for optimal growth in urine. Mutants that required leucine, methionine, serine, phenylalanine, or proline also exhibited reduced growth in urine. Several other nutritional mutants, including nicotinamide auxotrophs, which are found frequently among cystitis isolates, exhibited normal growth in urine.
摘要
用D-环丝氨酸富集法来鉴定在人尿液中生长受限的大肠杆菌营养缺陷型突变体。发现鸟嘌呤、精氨酸和谷氨酰胺的细菌合成对于在尿液中的最佳生长是必需的。需要亮氨酸、蛋氨酸、丝氨酸、苯丙氨酸或脯氨酸的突变体在尿液中的生长也有所减少。其他几种营养缺陷型突变体，包括在膀胱炎分离株中经常发现的烟酰胺营养缺陷型，在尿液中表现出正常生长。
相似文献
1
Nutritional requirements for growth of uropathogenic Escherichia coli in human urine.
Infect Immun. 1997 May;65(5):1960-1. doi: 10.1128/iai.65.5.1960-1961.1997.
2
Isolation of a nicotinamide-requiring clone of Escherichia coli O18:K1:H7 from women with acute cystitis: resemblance to strains found in neonatal meningitis.
Clin Infect Dis. 1993 Mar;16(3):412-6. doi: 10.1093/clind/16.3.412.
3
DsdX is the second D-serine transporter in uropathogenic Escherichia coli clinical isolate CFT073.
J Bacteriol. 2006 Sep;188(18):6622-8. doi: 10.1128/JB.00634-06.
4
Cross-feeding of Escherichia coli mutants defective in the biosynthesis of nicotinamide adenine dinucleotide.
J Bacteriol. 1973 Sep;115(3):982-6. doi: 10.1128/jb.115.3.982-986.1973.
5
Chemotaxis toward amino acids in Escherichia coli.
J Bacteriol. 1972 Oct;112(1):315-26. doi: 10.1128/jb.112.1.315-326.1972.
6
Characterization of Escherichia coli D-cycloserine transport and resistant mutants.
J Bacteriol. 2013 Apr;195(7):1389-99. doi: 10.1128/JB.01598-12. Epub 2013 Jan 11.
7
Nutritional requirements of mutants of Escherichia coli resistant to gamma irradiation.
Can J Microbiol. 1968 Jun;14(6):711-5. doi: 10.1139/m68-118.
8
Mechanism of D-cycloserine action: transport systems for D-alanine, D-cycloserine, L-alanine, and glycine.
J Bacteriol. 1970 Sep;103(3):778-88. doi: 10.1128/jb.103.3.778-788.1970.
9
Do temperature-sensitive auxotrophs of Escherichia coli have special virulence?
J Clin Microbiol. 1993 Jan;31(1):47-9. doi: 10.1128/jcm.31.1.47-49.1993.
10
Differential recovery of auxotrophs after penicillin enrichment in Escherichia coli.
J Bacteriol. 1971 May;106(2):297-300. doi: 10.1128/jb.106.2.297-300.1971.
引用本文的文献
1
Metabolomics survey of uropathogenic bacteria in human urine.
Front Microbiol. 2024 Dec 18;15:1507561. doi: 10.3389/fmicb.2024.1507561. eCollection 2024.
2
The Role of Metabolomics and Microbiology in Urinary Tract Infection.
Int J Mol Sci. 2024 Mar 8;25(6):3134. doi: 10.3390/ijms25063134.
3
Genome-wide identification of genes critical for fitness of multi-drug resistant porcine extraintestinal pathogenic by transposon-directed insertion site sequencing using a mouse infection model.
Virulence. 2023 Dec;14(1):2158708. doi: 10.1080/21505594.2022.2158708.
4
Proteomes of Uropathogenic Growing in Human Urine and in J82 Urinary Bladder Cells.
Proteomes. 2022 May 5;10(2):15. doi: 10.3390/proteomes10020015.
5
Genome-wide analysis of fitness-factors in uropathogenic during growth in laboratory media and during urinary tract infections.
Microb Genom. 2021 Dec;7(12). doi: 10.1099/mgen.0.000719.
6
Adaptation of Arginine Synthesis among Uropathogenic Branches of the Escherichia coli Phylogeny Reveals Adjustment to the Urinary Tract Habitat.
mBio. 2020 Sep 29;11(5):e02318-20. doi: 10.1128/mBio.02318-20.
7
Escherichia coli CFT073 Fitness Factors during Urinary Tract Infection: Identification Using an Ordered Transposon Library.
Appl Environ Microbiol. 2020 Jun 17;86(13). doi: 10.1128/AEM.00691-20.
8
Rapid Growth and Metabolism of Uropathogenic Escherichia coli in Relation to Urine Composition.
Clin Microbiol Rev. 2019 Oct 16;33(1). doi: 10.1128/CMR.00101-19. Print 2019 Dec 18.
9
Reaching the End of the Line: Urinary Tract Infections.
Microbiol Spectr. 2019 May;7(3). doi: 10.1128/microbiolspec.BAI-0014-2019.
10
Characterization of Asymptomatic Bacteriuria Isolates in Search of Alternative Strains for Efficient Bacterial Interference against Uropathogens.
Front Microbiol. 2018 Feb 14;9:214. doi: 10.3389/fmicb.2018.00214. eCollection 2018.
本文引用的文献
1
Mutants of Escherichia coli requiring methionine or vitamin B12.
J Bacteriol. 1950 Jul;60(1):17-28. doi: 10.1128/jb.60.1.17-28.1950.
2
Identification of two previously unrecognized genes (guaA and argC) important for uropathogenesis.
Mol Microbiol. 1996 Oct;22(2):217-29. doi: 10.1046/j.1365-2958.1996.00096.x.
3
Nitrogen control in bacteria.
Microbiol Rev. 1995 Dec;59(4):604-22. doi: 10.1128/mr.59.4.604-622.1995.
4
Do temperature-sensitive auxotrophs of Escherichia coli have special virulence?
J Clin Microbiol. 1993 Jan;31(1):47-9. doi: 10.1128/jcm.31.1.47-49.1993.
5
Observations on the growth of urethral and vaginal bacteria in sterile urine.
J Urol. 1980 Oct;124(4):461-3. doi: 10.1016/s0022-5347(17)55496-8.
6
Kinetic and genetic analyses of D-cycloserine inhibition and resistance in Escherichia coli.
J Bacteriol. 1965 Nov;90(5):1238-50. doi: 10.1128/jb.90.5.1238-1250.1965.
7
A theoretical and experimental analysis of bacterial growth in the bladder.
Mol Microbiol. 1992 Feb;6(4):555-62. doi: 10.1111/j.1365-2958.1992.tb01500.x.
8
Arginine auxotrophic phenotype of mutation in pyrA of Salmonella typhimurium: role of N-acetylornithine in the maturation of mutant carbamylphosphate synthetase.
J Bacteriol. 1978 May;134(2):528-36. doi: 10.1128/jb.134.2.528-536.1978.
Zotero 插件