Bastiaans M J, Nath N, Mazzur S
Vox Sang. 1979;37(3):129-38. doi: 10.1111/j.1423-0410.1979.tb02282.x.
A new antigenic specificity for HBsAg is described, and its usefulness as an epidemiological marker is discussed. This specificity, l, was found in specimens from all geographic areas studied (United States, Latin America, South Africa, the Solomon Islands, and New Guinea). In these areas, l was strongly associated with HBsAg/ay; y-positive, l-negative samples were observed only among specimens from United States volunteer blood donors. This determinant allowed a distinction of HBsAg/ad classes. Thus, the l determinant was detected in 51.4% of HBsAg/adw4, 44.1% of HBsAg/adw(non-w4), and 50% of HBsAg/adr. The association of l and other HBsAg determinants with HBeAg or anti-HBe was also investigated. HBeAg was found to be associated with the presence of the l determinant and with the r determinant. Anti-HBe was associated with the presence of the d and w determinants and with the absence of the l specificity.
本文描述了乙肝表面抗原（HBsAg）一种新的抗原特异性，并讨论了其作为流行病学标志物的用途。这种特异性，即l，在所有研究的地理区域（美国、拉丁美洲、南非、所罗门群岛和新几内亚）的标本中均有发现。在这些地区，l与HBsAg/ay密切相关；仅在美国志愿献血者的标本中观察到y阳性、l阴性的样本。这一决定簇能够区分HBsAg/ad类别。因此，在51.4%的HBsAg/adw4、44.1%的HBsAg/adw（非w4）和50%的HBsAg/adr中检测到l决定簇。还研究了l和其他HBsAg决定簇与HBeAg或抗-HBe的关联。发现HBeAg与l决定簇和r决定簇的存在有关。抗-HBe与d和w决定簇的存在以及l特异性的缺失有关。
