Smith D W
Department of Pathology and Buehler Center on Aging, Northwestern University School of Medicine, Chicago, IL 60611-2611, USA.
Gerontologist. 1997 Apr;37(2):200-6. doi: 10.1093/geront/37.2.200.
This article is about the few humans who reach very old ages--here called "longevity outliers." They are a distinct group, with lower mortality rates than most of the population. Centenarians are human longevity outliers. They are more resistant to causes of death such as heart disease and cancer than those who die at younger ages. Inheritance of life span, the present condition of centenarians, and their causes of death are considered. The maximum human life span in the future will be affected, at least marginally, as more longevity outliers survive to challenge today's maximum of 121 years.
本文关注的是极少数活到极高年龄的人——这里称之为“长寿 outliers”。他们是一个独特的群体,死亡率低于大多数人群。百岁老人就是人类中的长寿 outliers。与那些较年轻时就去世的人相比,他们对诸如心脏病和癌症等死因更具抵抗力。文中探讨了寿命的遗传、百岁老人的现状以及他们的死因。随着更多长寿 outliers 存活下来挑战如今 121 岁的最长寿命纪录,未来人类的最长寿命至少会受到轻微影响。