Kassaee A, Bloch P, Yorke E, Altschuler M D, Rosenthal D I
University of Pennsylvania School of Medicine, Philadelphia, USA.
Med Dosim. 2000 Fall;25(3):127-31. doi: 10.1016/s0958-3947(00)00038-8.
When parallel opposed 6-MV x-ray beams are used for treatment of head and neck tumors, superficial tissues and lymphatics at shallow depths of < or =4 to 6 mm may be at cancer risk but receive less than full radiation dose. In these cases, the use of either a beam spoiler or bolus material can increase dose to superficial tissues. The potential benefit of a beam spoiler relative to bolus is preservation of skin-sparing characteristics for cases in which the skin surface does not require full dose. In this study, we evaluate the application of a beam spoiler and compare it to bolus for standard treatments of head and neck tumors. Measurements of both depth dose in-water and in-air profiles were made with a beam spoiler for a 6-MV photon beam. The measurements were combined with Monte Carlo calculations to obtain the energy spectrum of the spoiler-generated electrons. An in-house pencil beam treatment-planning algorithm was used to calculate the dose distribution with spoiler. The dose distribution in the buildup region was then studied with and without the spoiler for a typical head and neck treatment with parallel-opposed beams. Dose distributions and partial-volume dose histograms (PVDH) demonstrate the benefits provided by spoilers for the head and neck treatments and the limitations of their use. The beam spoiler is useful in treating the superficial lymphatics in the buildup region near head and neck tumors. Guidelines for use of beam spoiler versus bolus are discussed.
当使用平行相对的6兆伏X射线束治疗头颈部肿瘤时,深度小于或等于4至6毫米的浅表组织和淋巴管可能有患癌风险,但接受的辐射剂量不足。在这些情况下,使用射野均整器或组织等效填充物可增加浅表组织的剂量。相对于组织等效填充物,射野均整器的潜在优势在于,对于皮肤表面不需要全剂量照射的情况,它能保持皮肤 sparing特性。在本研究中,我们评估了射野均整器的应用,并将其与组织等效填充物用于头颈部肿瘤的标准治疗进行比较。使用射野均整器对6兆伏光子束进行了水中深度剂量和空气中剂量分布的测量。这些测量结果与蒙特卡洛计算相结合,以获得均整器产生的电子的能谱。使用内部铅笔束治疗计划算法计算使用均整器时的剂量分布。然后,针对典型的平行相对束头颈部治疗,研究有无均整器时在剂量建成区的剂量分布。剂量分布和部分体积剂量直方图(PVDH)展示了均整器对头颈部治疗的益处及其使用的局限性。射野均整器在治疗头颈部肿瘤附近剂量建成区的浅表淋巴管方面很有用。讨论了使用射野均整器与组织等效填充物的指导原则。