Ozdemirler G, Oztezcan S, Toker G, Uysal M
Department of Biochemistry, Istanbul, Faculty of Medicine, University of Istanbul, Turkey.
Int J Vitam Nutr Res. 1997;67(2):130-3.
Erythrocyte diene conjugate levels and glutathione peroxidase and superoxide dismutase activities were found unchanged in hypercholesterolemic subjects with plasma cholesterol levels of 240 mg/dl as compared to normocholesterolemics (below 200 mg/dl). However, the susceptibility of VLDL + LDL, apolipoprotein B containing lipoproteins to copper-induced peroxidation and plasma endogenous malondialdehyde levels were increased in hypercholesterolemics. These results indicate that hypercholesterolemia is associated with increased susceptibility of VLDL + LDL to lipid peroxidation.
