Sponheim S R, Iacono W G, Clementz B A, Beiser M
Psychology Service (116B), Veterans Affairs Medical Center, Minneapolis, MN 55417, USA.
Biol Psychiatry. 1997 May 15;41(10):1020-7. doi: 10.1016/S0006-3223(96)00184-9.
To determine the association between season of birth and electroencephalogram (EEG) power abnormalities in schizophrenia, this study examined the resting EEGs of 28 winter-born and 81 nonwinter-born schizophrenia patients. Eighteen winter-born and 58 nonwinter-born nonschizophrenic psychosis patients (e.g., bipolar disorder patients with psychotic features), and 97 normal subjects were also studied. Compared to normal subjects, nonwinter-born schizophrenia patients had augmented low-frequency power and diminished alpha band power, but winter-born schizophrenia patients failed to have any EEG power abnormalities. Nonwinter-born nonschizophrenic psychosis patients had the same low-frequency and alpha band power abnormalities as nonwinter-born schizophrenia patients. The winter-born non-schizophrenic psychosis group failed to show any EEG power abnormalities. The results of this study indicate that in psychosis the functional characteristics of the brain vary depending on the season in which a person is born. Low-frequency and alpha band EEG power abnormalities may help distinguish psychosis stemming from a seasonally varying pathogen from psychosis of other etiologies.
为了确定精神分裂症患者的出生季节与脑电图（EEG）功率异常之间的关联，本研究检查了28名冬季出生和81名非冬季出生的精神分裂症患者的静息脑电图。还研究了18名冬季出生和58名非冬季出生的非精神分裂症性精神病患者（例如，具有精神病特征的双相情感障碍患者）以及97名正常受试者。与正常受试者相比，非冬季出生的精神分裂症患者低频功率增强，α波段功率降低，但冬季出生的精神分裂症患者未出现任何脑电图功率异常。非冬季出生的非精神分裂症性精神病患者与非冬季出生的精神分裂症患者具有相同的低频和α波段功率异常。冬季出生的非精神分裂症性精神病组未显示任何脑电图功率异常。本研究结果表明，在精神病中，大脑的功能特征因出生季节而异。低频和α波段脑电图功率异常可能有助于区分由季节性变化的病原体引起的精神病与其他病因的精神病。
