Abrams R, Taylor M A
Biol Psychiatry. 1980 Dec;15(6):871-8.
We investigated the relationship between EEG abnormalities and clinical psychopathological features in a consecutive sample of 159 patients who satisfied our research criteria for schizophrenia or affective disorder and in whom an EEG was obtained. In the 44 patients with abnormal EEGs, we found significant correlations between left-sided EEG abnormality and the clinical features of formal thought-disorder and emotional blunting, correlations which were independent of the variance associated with age, sex, past or present drug administration, or research diagnosis. The correlation for formal thought-disorder was specifically related to the left temporal lobe, a finding which we discuss in terms of the similarity between formal thought-disorder defined as a language dysfunction and fluent posterior aphasia. Because of the small sample size these results, although statistically significant, should be interpreted with caution and require confirmation by other workers.
我们对159例符合我们关于精神分裂症或情感障碍研究标准且已进行脑电图（EEG）检查的患者进行了连续抽样，以研究EEG异常与临床精神病理学特征之间的关系。在44例EEG异常的患者中，我们发现左侧EEG异常与形式思维障碍及情感迟钝的临床特征之间存在显著相关性，这些相关性独立于与年龄、性别、既往或当前用药情况或研究诊断相关的方差。形式思维障碍的相关性尤其与左侧颞叶有关，鉴于形式思维障碍被定义为一种语言功能障碍，与流利型后部失语症相似，我们将对此发现进行讨论。由于样本量较小，尽管这些结果具有统计学意义，但仍应谨慎解释，并且需要其他研究人员予以证实。
