Garel M, Stark C, Blondel B, Lefebvre G, Vauthier-Brouzes D, Zorn J R
Epidemiology Research Unit on Women's and Children's Health, INSERM U 149, Villejuif, France.
Hum Reprod. 1997 Mar;12(3):617-22. doi: 10.1093/humrep/12.3.617.
This study had two objectives. Firstly we assessed the effects of multifetal pregnancy reduction on the mothers' emotional well-being and the relationship with the children during the 2 years following intervention. Secondly at 2 years we compared mothers who had a reduction with mothers who had not and had delivered triplets. The comparisons focused on the mothers' health and their relationship with the children. Women having had a reduction in two hospitals in Paris, between May 1992 and June 1993, were contacted just after intervention for a prospective study. In all, 18 women were included. At 1 and 2 years, 10 women participated. At 2 years, 10 additional women were included. The answers of these 20 mothers were compared to those of 11 consecutive mothers of 2 year old triplets, assessed by the same psychologist in a previous prospective study. Semi-structured interviews were conducted at home. The mothers' social characteristics, their parity, the children's condition at birth and 4 months were very similar between the reduction and triplet groups. One year after birth one-third of the women in the reduction group reported persistent depressive symptoms related to the reduction, mainly sadness and guilt. The others made medical and rational comments expressing no emotion. At 2 years all but two women seemed to have overcome the emotional pain associated with the reduction. The comparison with mothers of triplets indicated that the mothers' anxiety and depression, and difficult relationship with the children were less acute in the reduction group. These results presented some limitations, since a high number of women who miscarried or refused to participate in the follow-up were not assessed at 1 and 2 years. However, a majority of women who participated in the study 2 years after intervention seemed able to accept a multifetal pregnancy reduction to achieve parental goals.
本研究有两个目标。首先,我们评估了多胎妊娠减胎术对母亲情绪健康的影响以及干预后两年内与孩子的关系。其次,在两年时,我们将接受减胎术的母亲与未接受减胎术且分娩三胞胎的母亲进行了比较。比较重点在于母亲的健康状况及其与孩子的关系。1992年5月至1993年6月期间在巴黎两家医院接受减胎术的女性在干预后不久就被联系参与一项前瞻性研究。总共纳入了18名女性。在1年和2年时,有10名女性参与。在2年时,又纳入了10名女性。将这20位母亲的回答与11位连续分娩2岁三胞胎母亲的回答进行比较,这些三胞胎母亲在之前一项前瞻性研究中由同一位心理学家进行评估。在家中进行了半结构化访谈。减胎组和三胞胎组母亲的社会特征、产次、孩子出生时和4个月时的状况非常相似。出生一年后,减胎组三分之一的女性报告了与减胎术相关的持续性抑郁症状,主要是悲伤和内疚。其他人则做出了客观理性的评论,未表达情绪。到2年时,除两名女性外,其他所有人似乎都已克服了与减胎术相关的情感痛苦。与三胞胎母亲的比较表明,减胎组母亲的焦虑和抑郁以及与孩子的困难关系没那么严重。这些结果存在一些局限性,因为大量流产或拒绝参与随访的女性在1年和2年时未被评估。然而,干预后两年参与研究的大多数女性似乎能够接受多胎妊娠减胎术以实现为人父母的目标。