Yamauchi H, Shiraki M, Otani M, Matsuo M, Orimo H
Endocrinol Jpn. 1977 Jun;24(3):281-5. doi: 10.1507/endocrj1954.24.281.
Stability of [Asu1,7]-eel calcitonin was compared with that of eel calcitonin by the radioimmunoassay method. [Asu1,7]-Eel calcitonin cross-reacted with anti-eel calcitonin antisera. [Asu1,7]-Eel calcitonin was as stable as eel calcitonin in rabbit liver or rabbit kidney extracts when incubated at 37 degrees C. Disappearance curves from the plasma of [Asu1,7]-eel calcitonin and eel calcitonin following iv injection in rabbits were quite similar.
通过放射免疫分析法比较了[1,7位天冬氨酸]-鳗鱼降钙素与鳗鱼降钙素的稳定性。[1,7位天冬氨酸]-鳗鱼降钙素与抗鳗鱼降钙素抗血清发生交叉反应。当在37℃孵育时,[1,7位天冬氨酸]-鳗鱼降钙素在兔肝或兔肾提取物中的稳定性与鳗鱼降钙素相同。静脉注射给兔子后,[1,7位天冬氨酸]-鳗鱼降钙素和鳗鱼降钙素在血浆中的消失曲线非常相似。