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大鼠和小鼠包皮腺某些特殊脂质及其激素影响的研究。

Studies on some unusual lipids of the preputial glands of rats and mice and their hormonal influence.

作者信息

Mukherjea M

出版信息

Endokrinologie. 1977 Jul;69(2):136-42.

PMID:913341
Abstract

Major neutral lipid fractions of the preputial glands of mice have been identified by analytical and preparative thin layer chromatography (TLC) and gas liquid chromatography (GLC) as wax esters, neutral plasmalogen, alkyl diglyceride, triglyceride and cholesterol. An unusual lipid fraction between wax esters and neutral plasmalogens was identified as alkyl acetate, which has been reported earlier to function as sex attractant. The lipid pattern of the preputial glands of rats in both sexes was similarly studied. Three unknown bands of lipids were identified by TLC between wax ester and alk-1-enyl diglycerides, which on further analysis by GLC and infrared spectroscopy gave preliminary indication of aliphatic diester waxes. Administration of androgen stimulated the biosynthesis of these substances.

摘要

通过分析型和制备型薄层色谱法(TLC)以及气液色谱法(GLC),已鉴定出小鼠包皮腺中的主要中性脂质成分包括蜡酯、中性缩醛磷脂、烷基甘油二酯、甘油三酯和胆固醇。在蜡酯和中性缩醛磷脂之间发现了一种不寻常的脂质成分,被鉴定为乙酸烷基酯,此前已有报道称其具有性引诱剂的功能。对大鼠两性的包皮腺脂质模式进行了类似研究。通过TLC在蜡酯和1-烯基甘油二酯之间鉴定出三条未知脂质带,通过GLC和红外光谱进一步分析,初步表明为脂肪族二酯蜡。雄激素的给药刺激了这些物质的生物合成。

相似文献

1
Studies on some unusual lipids of the preputial glands of rats and mice and their hormonal influence.大鼠和小鼠包皮腺某些特殊脂质及其激素影响的研究。
Endokrinologie. 1977 Jul;69(2):136-42.
2
The hormonal induction of alkyl glycerol, wax and alkyl acetate synthesis in the preputial gland of the mouse.小鼠包皮腺中烷基甘油、蜡和乙酸烷基酯合成的激素诱导作用。
Biochim Biophys Acta. 1972 Jan 27;260(1):35-40. doi: 10.1016/0005-2760(72)90071-9.
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Effect of alpha-melanocyte-stimulating hormone and testosterone on cutaneous and modified sebaceous glands in the rat.α-黑素细胞刺激素和睾酮对大鼠皮肤及改良皮脂腺的作用。
J Endocrinol. 1976 Dec;71(3):279-88. doi: 10.1677/joe.0.0710279.
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Glyceryl ether, wax ester and triglyceride composition of the mouse preputial gland.小鼠包皮腺的甘油醚、蜡酯和甘油三酯成分。
Lipids. 1969 Nov;4(6):435-40. doi: 10.1007/BF02531019.
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Proceedings: Synergistic effects of testosterone and alpha-melanocyte-stimulating hormone on lipogenesis in rat preputial gland.论文集:睾酮与α-黑素细胞刺激素对大鼠包皮腺脂肪生成的协同作用
J Endocrinol. 1975 Mar;64(3):63P.
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Testosterone induction of microsomal acyl-CoA reductase and a cytosolic regulatory protein in mouse preputial glands.睾酮对小鼠包皮腺微粒体酰基辅酶A还原酶和一种胞质调节蛋白的诱导作用。
Biochim Biophys Acta. 1986 Jan 3;875(1):129-32. doi: 10.1016/0005-2760(86)90020-2.
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Long-chain alkyl acetates in the preputial gland of the mouse.
Biochim Biophys Acta. 1969 Dec 30;192(3):516-21. doi: 10.1016/0304-4165(69)90401-2.
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Inhibitory effect of propranolol on lipid synthesis in gonadectomized male hamster flank organs.普萘洛尔对去性腺雄性仓鼠胁腹器官脂质合成的抑制作用。
Arch Med Res. 1998 Winter;29(4):291-5.
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Steroids. 1997 Dec;62(12):782-8. doi: 10.1016/s0039-128x(97)00091-3.
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Hormonal influences on the morphogenesis of the preputial gland of embryonic mice.激素对胚胎小鼠包皮腺形态发生的影响。
Anat Rec. 1975 Jan;181(1):35-53. doi: 10.1002/ar.1091810104.

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