Nĕmec J, Smejkal V
Eur J Nucl Med. 1977 Sep 30;2(3):143-6. doi: 10.1007/BF00257270.
Two AFTNs in one thyroid lobe were detected in a eumetabolic woman, with complete suppression of uptake in the paranodular tissue. After TSH stimulation, performed 2 months later, uptake was found in paranodular tissue only, both nodules being cold on the 131I scan. The same distribution of 131I was found on the next scan after a further 2 months without stimulation. Cystic degeneration was found by sonography and confirmed by aspiration biopsy. The destruction of one of the AFTNs was incomplete, as witnessed by a reappearance of function after 16 months. No differences in the thyroid handling of pertechnetate and iodide were detected. It is believed that the TSH stimulation might have hastened the otherwise spontaneous degenerative changes in the AFTNs.
在一名甲状腺功能正常的女性的一个甲状腺叶中检测到两个自主性功能性甲状腺结节（AFTNs），结节旁组织摄取完全受抑制。两个月后进行促甲状腺激素（TSH）刺激，结果发现仅在结节旁组织有摄取，两个结节在131I扫描中均为冷结节。在未进行刺激的另外两个月后的下一次扫描中，发现131I的分布相同。超声检查发现有囊性变，并经穿刺活检证实。其中一个AFTN的破坏不完全，16个月后功能再次出现就是证明。未检测到高锝酸盐和碘化物在甲状腺摄取方面的差异。据信，TSH刺激可能加速了AFTNs原本会自然发生的退行性变化。
