Ellwein L B, Drummond M F
University of York.
Int J Technol Assess Health Care. 1996 Fall;12(4):691-7. doi: 10.1017/s0266462300010977.
Clinical trial randomization schemes to control patient characteristics that can influence clinical response are not sufficient to control for their effects on operational efficiency and cost within the provider institution. This variation can result in biased economic findings when patients are allowed to select a provider themselves.
用于控制可能影响临床反应的患者特征的临床试验随机方案,不足以控制这些特征对医疗机构内部运营效率和成本的影响。当允许患者自行选择医疗机构时,这种差异可能导致有偏差的经济研究结果。