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[持续性房性心动过速与围产期心肌病——一项治疗挑战]

[Incessant atrial tachycardia and peripartum cardiomyopathy--a therapeutic challenge].

作者信息

Brito D, de Lacerda A P, Freitas P, Costa e Silva Z, Bento H, de Sousa J, Fiuza M, Lopes M G, Barbosa M, França C

机构信息

Unidade de Cuidados Intensivos Polivalentes, Hospital Universitário de Sta. Maria, Lisboa.

出版信息

Rev Port Cardiol. 1997 Feb;16(2):157-63, 124.

PMID:9138464
Abstract

Peripartum cardiomyopathy is an uncommon cause of heart failure but with serious prognosis. We report the case of a patient with peripartum cardiomyopathy presenting acute heart failure (severe biventricular systolic failure) and incessant atrial tachycardia, a rare arrhythmia difficult to control, that was responsible for cardiogenic shock, fetus death and multiple organ failure: renal failure (hemodialysis during 17 days), respiratory and hepatic failure and ischemic acute cholecystitis (treated surgically). After emergency cesarean section, heart rate control was obtained only after administering verapamil. Progressive clinical improvement with total recovery of hepatic and renal functions followed under treatment with vigorous multiple organ support. Six months after referral, the patients is doing well with normal daily life controlled with conventional therapy for heart failure, in stable sinus rhythm. Echocardiography shows a dilated left ventricle with partial resolution of systolic dysfunction rhythm. Echocardiography shows a dilated left ventricle with partial resolution of systolic dysfunction. The use of verapamil in severe biventricular systolic failure is discussed.

摘要

围产期心肌病是心力衰竭的一种罕见病因,但预后严重。我们报告一例围产期心肌病患者,其出现急性心力衰竭(严重双心室收缩功能衰竭)和持续性房性心动过速,这是一种难以控制的罕见心律失常,导致心源性休克、胎儿死亡和多器官功能衰竭:肾衰竭(17天血液透析)、呼吸和肝功能衰竭以及缺血性急性胆囊炎(手术治疗)。紧急剖宫产术后,仅在给予维拉帕米后心率才得到控制。在积极的多器官支持治疗下,临床逐渐改善,肝肾功能完全恢复。转诊六个月后,患者情况良好,日常生活正常,采用常规心力衰竭治疗控制,窦性心律稳定。超声心动图显示左心室扩张,收缩功能障碍部分缓解。本文讨论了维拉帕米在严重双心室收缩功能衰竭中的应用。

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