[Studies of transketolase activity in the kidney and the ultrastructure of liver cells of the Rainbow trout (Salmo gairdneri) on an energy rich, thiamine-free diet].

The liver cells of Rainbow trouts (Salmo Gairdneri) were examined with electron-microscopic methods. The animals were fed for 30, 60 or 100 days with a thiaminefree diet. After such a treatment, the mitochondria are swollen in the hepatocytes, the ER often is destroyed and there are large autophagosomes. The effects were the clearer the longer the time of thiaminefree feeding. The activity of transketolase (as an indicator for the supply with thiamine) in the kidney was decreased all the longer the time of thiaminefree feeding. These effects were significant.