Obasohan A O, Ajuyah C O
Department of Medicine, Uniben/UBTH, Benin City, Nigeria.
J Hum Hypertens. 1996 Dec;10(12):801-4.
Hypertension is regarded as the most common cause of heart failure in Nigeria and other Black African countries. A few reports suggest that heart failure due to hypertension hardly occurs without the presence of an extra burden on the heart from the presence of other cardiac risk factors. This study assesses the occurrence of other potential causes of heart failure in 55 consecutive admitted cases of hypertensive heart failure. All but six cases (88%) were associated with the presence of one or other significant cardiac risk factors while 56.2% were associated with multiple heart failure risk factors. Five of the six were poor drug compliers. Of the six, only one was completely free of cardiac risk factors and he was unaware of his hypertension and so had never had therapy. The others either consumed alcohol moderately, had mild renal impairment or were grossly obese. The factors found were anaemia, renal dysfunction, abnormal glucose tolerance, alcoholic ingestion and co-existing valvular heart disease. The finding shows that among Nigerian patients hospitalised for hypertensive heart failure, heart failure was rare in those hypertensive patients who had no extra cardiac burden, and therefore control of these factors will help prevent the development of heart failure in hypertension with its dismal prognosis.
高血压被认为是尼日利亚和其他非洲黑人国家心力衰竭最常见的病因。一些报告表明,在没有其他心脏危险因素给心脏带来额外负担的情况下,因高血压导致的心力衰竭几乎不会发生。本研究评估了55例连续收治的高血压性心力衰竭患者中其他潜在心力衰竭病因的发生情况。除6例(88%)外,所有病例均与一种或多种重要的心脏危险因素有关,而56.2%与多种心力衰竭危险因素有关。6例中有5例药物依从性差。6例中只有1例完全没有心脏危险因素,他不知道自己患有高血压,因此从未接受过治疗。其他患者要么适度饮酒,要么有轻度肾功能损害,要么严重肥胖。发现的因素有贫血、肾功能不全、糖耐量异常、酒精摄入和并存的瓣膜性心脏病。研究结果表明,在因高血压性心力衰竭住院的尼日利亚患者中,没有额外心脏负担的高血压患者很少发生心力衰竭,因此控制这些因素将有助于预防高血压患者发生心力衰竭及其不良预后。