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[不育婚姻的诊断与治疗。对500对无子女夫妇不育情况的回顾性研究]

[Diagnosis and therapy of sterile marriages. Retrospective studies on the sterility of 500 childless couples].

作者信息

Schmidt-Elmendorff H, Scheulen R

出版信息

Fortschr Med. 1977 Oct 20;95(39):2375-81.

PMID:914196
Abstract

In the retrospective analysis of 500 involuntarily childless couples the following results were observed: The pregnancy rate was 37.2%. The age of the women did not influence the conception rate significantly. Women with a sterility of less than 5 years duration had a statistically higher conception rate than those with longer lasting sterility. Patients with oligomenorrhea had a significantly higher pregnancy rate than those with normal menstrual cycle. Cyclofenil therapy resulted in a significantly higher conception rate than treatment without ovulation inducing compounds. Homologeous insemination had a pregnancy rate of 25,4%. The additional therapy with ovulation inducers did not influence the results significantly. Patients with uterine hypoplasia had a significantly higher conception rate than women with normal uterine size. Women who showed uterine hypoplasia before sterility treatment had taken oral contraceptives less often than women with normal uterine size. There was a significant correlation between uterine hypoplasia and cyclic disorders. Women with cyclic disorders had hirsutism more often than those with a normal cycle. In cases with normal sperm count (40 mill./ml) there was a significantly better pregnancy rate than in those with oligozoospermia (40 mill./ml). In cases of sperm motility of over 70% a significantly higher pregnancy rate was observed than in those with a motility below 70%. In spermiograms with more than 70% of normally configurated sperms the results were significantly better than in those with less than 70% normal sperms.

摘要

在对500对非自愿无子女夫妇的回顾性分析中,观察到以下结果:妊娠率为37.2%。女性年龄对受孕率没有显著影响。不育时间少于5年的女性受孕率在统计学上高于不育时间更长的女性。月经过少的患者妊娠率显著高于月经周期正常的患者。克罗米芬治疗导致的受孕率显著高于未使用促排卵化合物的治疗。同种异体授精的妊娠率为25.4%。使用促排卵剂的附加治疗对结果没有显著影响。子宫发育不全的患者受孕率显著高于子宫大小正常的女性。在不育治疗前表现出子宫发育不全的女性口服避孕药的频率低于子宫大小正常的女性。子宫发育不全与周期紊乱之间存在显著相关性。周期紊乱的女性多毛症的发生率高于周期正常的女性。精子计数正常(4000万/毫升)的病例妊娠率显著高于少精子症(<4000万/毫升)的病例。精子活力超过70%的病例观察到的妊娠率显著高于活力低于70%的病例。正常形态精子超过70%的精液分析结果显著优于正常精子低于70%的结果。

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Fortschr Med. 1977 Oct 20;95(39):2375-81.
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