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生存分析中的删失问题。

Censoring issues in survival analysis.

作者信息

Leung K M, Elashoff R M, Afifi A A

机构信息

Department of Biostatistics, School of Public Health, University of California, Los Angeles 90095, USA.

出版信息

Annu Rev Public Health. 1997;18:83-104. doi: 10.1146/annurev.publhealth.18.1.83.

Abstract

A key characteristic that distinguishes survival analysis from other areas in statistics is that survival data are usually censored. Censoring occurs when incomplete information is available about the survival time of some individuals. We define censoring through some practical examples extracted from the literature in various fields of public health. With few exceptions, the censoring mechanisms in most observational studies are unknown and hence it is necessary to make assumptions about censoring when the common statistical methods are used to analyze censored data. In addition, we present situations in which censoring mechanisms can be ignored. The effects of the censoring assumptions are demonstrated through actual studies.

摘要

生存分析与统计学其他领域相区别的一个关键特征是生存数据通常是截尾的。当关于某些个体的生存时间信息不完整时,就会出现截尾情况。我们通过从公共卫生各个领域的文献中提取的一些实际例子来定义截尾。除了少数例外情况,大多数观察性研究中的截尾机制是未知的,因此当使用常见统计方法分析截尾数据时,有必要对截尾情况做出假设。此外,我们还介绍了可以忽略截尾机制的情形。通过实际研究展示了截尾假设的影响。

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