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膀胱内灌注在膀胱浅表性移行细胞癌治疗和预防中的作用的当前概念。芬兰膀胱研究小组。

Current concepts in the role of intravesical instillations in the therapy and prophylaxis of superficial transitional-cell cancer of the bladder. The Finnbladder Research Group.

作者信息

Alfthan O, Jauhiainen K, Kaasinen E, Liukkonen T

机构信息

Department of Urology, Helsinki University Central Hospital, Finland.

出版信息

World J Urol. 1997;15(2):89-95. doi: 10.1007/BF02201978.

DOI:10.1007/BF02201978
PMID:9144897
Abstract

A survey on superficial, local urinary bladder cancer, its prognostic factors, and instillation treatments is presented on the basis of experience with approximately 1,000 patients over a period of 20 years, experimental investigations, and the literature. Personal opinions and practical recommendations are presented in 11 conclusive theses.

摘要

基于20年间对约1000例患者的经验、实验研究及文献，本文对浅表性局部膀胱癌、其预后因素及灌注治疗进行了综述。在11条结论性论点中给出了个人观点及实用建议。

相似文献

1
Current concepts in the role of intravesical instillations in the therapy and prophylaxis of superficial transitional-cell cancer of the bladder. The Finnbladder Research Group.膀胱内灌注在膀胱浅表性移行细胞癌治疗和预防中的作用的当前概念。芬兰膀胱研究小组。
World J Urol. 1997;15(2):89-95. doi: 10.1007/BF02201978.
2
[Intravesical instillation in the treatment of superficial tumors of the bladder].
Prog Urol. 1998 Apr;8(2):268-73.
3
Efficacy of immediate instillation combined with regular instillations of pirarubicin for Ta and T1 transitional cell bladder cancer after transurethral resection: a prospective, randomized, multicenter study.经尿道电切术后即刻灌注联合定期灌注吡柔比星治疗 Ta、T1 移行细胞膀胱癌的疗效：一项前瞻性、随机、多中心研究。
Chin Med J (Engl). 2013;126(15):2805-9.
4
A phase II study of prophylactic intravesical chemotherapy with epirubicin in the treatment of superficial bladder cancer. Tokyo Women's Medical College Bladder Cancer Collaborating Group.表柔比星预防性膀胱内化疗治疗浅表性膀胱癌的II期研究。东京女子医科大学膀胱癌协作组。
Cancer Chemother Pharmacol. 1994;35 Suppl:S60-4. doi: 10.1007/BF00686922.
5
Phase II study of intravesical chemoprophylaxis of epirubicin after transurethral resection of bladder tumors. Tottori University Oncology Group.
Cancer Chemother Pharmacol. 1994;35 Suppl:S57-9. doi: 10.1007/BF00686921.
6
Rationale for intravesical chemotherapy in the treatment and prophylaxis of superficial transitional cell carcinoma.膀胱内化疗在浅表性移行细胞癌治疗和预防中的原理。
Prog Clin Biol Res. 1989;310:215-36.
7
Intravesical chemotherapy prophylaxis in primary superficial bladder cancer: a meta-analysis of 3703 patients from 11 randomized trials.原发性浅表性膀胱癌的膀胱内化疗预防：来自11项随机试验的3703例患者的荟萃分析。
J Clin Epidemiol. 2000 Jul;53(7):676-80. doi: 10.1016/s0895-4356(99)00203-6.
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Sustained prophylactic effect of intravesical bacille Calmette-Guérin for superficial bladder cancer: a smoothed hazard analysis in a randomized prospective study.卡介苗膀胱灌注对浅表性膀胱癌的持续预防作用：一项随机前瞻性研究中的平滑风险分析
Urology. 2006 Mar;67(3):545-9. doi: 10.1016/j.urology.2005.09.045.
9
Intravesical chemoprophylaxis of superficial transitional cell carcinoma of the bladder. When should the drug be given?
Prog Clin Biol Res. 1985;185B:47-55.
10
Prospective phase II trial of alternating intravesical Bacillus Calmette-Guérin (BCG) and interferon alpha IIB in the treatment and prevention of superficial transitional cell carcinoma of the urinary bladder: preliminary results.卡介苗（BCG）与干扰素α-IIB交替膀胱灌注治疗和预防浅表性膀胱移行细胞癌的前瞻性II期试验：初步结果
J Surg Oncol. 2000 Jul;74(3):181-4. doi: 10.1002/1096-9098(200007)74:3<181::aid-jso3>3.0.co;2-f.

本文引用的文献

1
Intra-urothelial cancer: carcinoma in situ, Bowen's disease of the urinary system: discussion of thirty cases.尿路上皮内癌：原位癌，泌尿系统鲍恩病：30例病例讨论
J Urol. 1952 Oct;68(4):763-72. doi: 10.1016/S0022-5347(17)68279-X.
2
Immunoreactivity of bcl-2, p53 and EGFr is associated with tumor stage, grade and cell proliferation in superficial bladder cancer. Finnbladder III Group.
Urol Res. 1997;25(1):1-7. doi: 10.1007/BF00941899.
3
Expression of MIB-1, mitotic index and S-phase fraction as indicators of cell proliferation in superficial bladder cancer. Finnbladder Group.
Urol Res. 1996;24(1):61-6. doi: 10.1007/BF00296736.
4
Alternating mitomycin C and bacillus Calmette-Guerin instillation prophylaxis for recurrent papillary (stages Ta to T1) superficial bladder cancer. Finnbladder Group.丝裂霉素C与卡介苗交替灌注预防复发性乳头状（Ta至T1期）浅表性膀胱癌。芬兰膀胱研究组。
J Urol. 1996 Jul;156(1):56-9; discussion 59-60.
5
Bacillus Calmette-Guérin sensitises fresh transitional carcinoma cells and T24 cell line to non-MHC-restricted cytotoxicity in vitro.卡介苗在体外使新鲜的移行癌细胞和T24细胞系对非主要组织相容性复合体（MHC）限制的细胞毒性敏感。
Br J Urol. 1993 Dec;72(6):897-906. doi: 10.1111/j.1464-410x.1993.tb16293.x.
6
Prediction of cancer incidence in the Nordic countries up to the years 2000 and 2010. A collaborative study of the five Nordic Cancer Registries.北欧国家截至2000年和2010年癌症发病率的预测。北欧五个癌症登记处的合作研究。
APMIS Suppl. 1993;38:1-124.
7
Cytostatic effect of interferon alpha on human bladder cancer cells in vitro. A flow cytometric study.干扰素α对人膀胱癌细胞的体外细胞生长抑制作用。一项流式细胞术研究。
Ann Chir Gynaecol Suppl. 1993;206:50-3.
8
Dissecting the immunobiological effects of Bacillus Calmette-Guérin (BCG) in vitro: evidence of a distinct BCG-activated killer (BAK) cell phenomenon.体外剖析卡介苗（BCG）的免疫生物学效应：一种独特的卡介苗激活杀伤（BAK）细胞现象的证据。
J Urol. 1993 Dec;150(6):1932-7. doi: 10.1016/s0022-5347(17)35941-4.
9
Reduced expression of retinoblastoma (Rb) gene protein is related to cell proliferation and prognosis in transitional-cell bladder cancer.视网膜母细胞瘤（Rb）基因蛋白表达降低与移行细胞膀胱癌的细胞增殖及预后相关。
J Cancer Res Clin Oncol. 1995;121(1):44-50. doi: 10.1007/BF01202728.
10
Impact of tumour grade, stage, number and size, and smoking and sex, on survival in patients with transitional cell carcinoma of the bladder.肿瘤分级、分期、数量和大小以及吸烟与性别对膀胱移行细胞癌患者生存率的影响。
Br J Urol. 1995 Oct;76(4):470-4. doi: 10.1111/j.1464-410x.1995.tb07748.x.