Wong P Y, Doran T A, Ho F F, Mee A V
Clin Chem. 1979 Nov;25(11):1905-8.
We evaluated four immunoassay methods for determination of alpha-fetoprotein in serum. All are commercially available in kit form in North American and we find them acceptable with respect to sensitivity, stability, precision, linearity, and analytical recovery. For the Dainabott method, the median values from 16 through 20 weeks of gestation are 34.4, 38.1, 42.1, 51.4, and 66.3 micrograms/L for each week, respectively. Corresponding values for the Amersham method are 27.9, 31.4, 34.9, 38.2, and 54.0 micrograms/L, respectively. For the Behring-RIA method they are 33.4, 37.4, 39.4, 49.9, and 66.3 micrograms/L, respectively. Results for four cases of confirmed neural tube defects are presented.
我们评估了四种用于测定血清中甲胎蛋白的免疫测定方法。在北美，所有这些方法都有试剂盒形式的商业产品，并且我们发现它们在灵敏度、稳定性、精密度、线性和分析回收率方面是可接受的。对于戴纳博特方法，妊娠16至20周每周的中位数分别为34.4、38.1、42.1、51.4和66.3微克/升。安迈公司方法的相应值分别为27.9、31.4、34.9、38.2和54.0微克/升。对于贝林放射免疫分析法，它们分别为33.4、37.4、39.4、49.9和66.3微克/升。文中给出了4例确诊神经管缺陷病例的结果。
