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[使用帕金森病问卷(PDQ-39)评估帕金森病患者的生活质量。一项试点研究]

[Assessing quality of life in Parkinson's disease using the PDQ-39. A pilot study].

作者信息

Martínez-Martín P, Frades Payo B, Fontán Tirado C, Martínez Sarriés F J, Guerrero M T, del Ser Quijano T

机构信息

Sección de Neurología, Hospital de Getafes, Madrid.

出版信息

Neurologia. 1997 Feb;12(2):56-60.

PMID:9147452
Abstract

The aim of this pilot study was to analyze an adaptation of the PDQ-39, a Parkinson's disease (PD) quality of life questionnaire, for use in Spanish. Fifty patients were enrolled. Patient characteristics and medical histories were recorded, including scores on the following scales: Hoehn and Yahr (HY), PD unified (UPDRS), Schwab and England (SE), Intermediate Scale for Assessment of PD (ISAPD). Barthel Index (BI), Pfeiffer's SPMSQ, Global Deterioration Scale (GDS), Geriatric Depression Scale (GDS). Hospital Depression and Anxiety Scale (HDA) and the PDQ-39. Descríptive statistics were recorded, as well as Spearman's r and ANOVA results. The dimensions that correlated well with PD scale scores were mobility, daily life activities and cognitive deterioration. The dimension stigma correlated with complications on the UPDRS and the ISAPD. Emotional well-being correlated with subscale I of the UPDRS, the GDS and the HDA (r = 0.39-0.79, p < 0.01-0.001). Physical discomfort correlated only with depression and anxiety. Stage of disease and level of depression influenced most dimensions assessed by the PDQ-39. Some psychosocial factors that are important components of well-being are scarcely reflected by the clinical scales usually applied.

摘要

这项初步研究的目的是分析帕金森病(PD)生活质量问卷PDQ - 39的一个改编版本,以便在西班牙语环境中使用。招募了50名患者。记录了患者的特征和病史,包括以下量表的得分:霍恩和亚尔分级(HY)、帕金森病统一评分量表(UPDRS)、施瓦布和英格兰量表(SE)、帕金森病评估中间量表(ISAPD)、巴氏指数(BI)、 Pfeiffer简易精神状态问卷(SPMSQ)、总体衰退量表(GDS)、老年抑郁量表(GDS)、医院焦虑抑郁量表(HDA)以及PDQ - 39。记录了描述性统计数据以及斯皮尔曼相关系数r和方差分析结果。与帕金森病量表得分相关性良好的维度是运动能力、日常生活活动和认知衰退。耻辱感维度与UPDRS和ISAPD中的并发症相关。情绪幸福感与UPDRS的子量表I、GDS和HDA相关(r = 0.39 - 0.79,p < 0.01 - 0.001)。身体不适仅与抑郁和焦虑相关。疾病阶段和抑郁程度影响了PDQ - 39评估的大多数维度。一些作为幸福感重要组成部分的社会心理因素在通常应用的临床量表中几乎没有体现。

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J Parkinsons Dis. 2023;13(5):699-715. doi: 10.3233/JPD-230050.
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Reliability and validity of PDQ-39: a quality-of-life measure for patients with PD in China.PDQ-39 在中国人帕金森病患者中的信度和效度。
Qual Life Res. 2012 Sep;21(7):1217-21. doi: 10.1007/s11136-011-0026-1. Epub 2011 Oct 9.
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[Deep brain stimulation for Parkinson's disease].[帕金森病的脑深部电刺激术]
Nervenarzt. 2010 Jun;81(6):669-79. doi: 10.1007/s00115-010-2938-3.
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Health-related quality of life and healthcare utilisation in patients with Parkinson's disease: impact of motor fluctuations and dyskinesias.帕金森病患者的健康相关生活质量与医疗保健利用:运动波动和异动症的影响
Pharmacoeconomics. 2001;19(10):1013-38. doi: 10.2165/00019053-200119100-00004.
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Pharmacoeconomics. 1997 Oct;12(4):486-98. doi: 10.2165/00019053-199712040-00006.