Carod-Artal Francisco Javier, Martinez-Martin Pablo, Vargas Antonio Pedro
Department of Neurology, Sarah Network of Rehabilitation Hospitals, Sarah Hospital, Brasilia, Brazil.
Mov Disord. 2007 Jan;22(1):91-8. doi: 10.1002/mds.21216.
The objective of this study was to perform an independent validation of the Scales for Outcomes in Parkinson's Disease-Psychosocial questionnaire (SCOPA-PS) and assessment of the Parkinson's Disease Questionnaire (PDQ-39), Brazilian version. Patients were evaluated by means of the Unified Parkinson's Disease Rating Scale, Hoehn and Yahr staging (HY), Schwab and England scale, Mini-Mental State Examination, and Hospital Anxiety and Depression Scale. Health-related quality of life was evaluated using the MOS-Short Form 36 (SF-36), PDQ-39, and SCOPA-PS. One hundred forty-four patients were included (mean age, 62 years; 53.5% males; mean duration of illness, 6.6 years; HY, 1-4). Mean SCOPA-PS and PDQ-39 Summary Index (SI) were 39.2 and 40.7, respectively. The internal consistency of SCOPA-PS (Cronbach's alpha = 0.84; item-total correlation, 0.44-0.73) and PDQ-39 dimensions (alpha = 0.61-0.85; item-total correlation, 0.46-0.82) were satisfactory. Concerning the stability of the questionnaires, intraclass correlation coefficient (ICC) values were 0.71 for the SCOPA-PS and 0.86 for the PDQ-39 SI. ICC for PDQ-39 dimensions ranged from 0.52 (social support) to 0.80 (stigma). Standard error of measurement (SEM) values for each PDQ-39 dimension ranged from 0.49 (emotional well-being) to 17.52 (social support). SEM values for SCOPA-PS and PDQ-39 SI were 11.84 and 6.72, respectively. A significant correlation of SCOPA-PS and PDQ-39 SI with the SF-36 physical (-0.42 and -0.52, respectively) and mental components (-0.41) was found. Correlation between SCOPA-PS and PDQ-39 SI was 0.73 (all coefficients, P < 0.0001). The SCOPA-PS and PDQ-39, Brazilian versions, have satisfactory metric attributes.
本研究的目的是对帕金森病心理社会问卷（SCOPA-PS）进行独立验证，并对巴西版帕金森病问卷（PDQ-39）进行评估。通过统一帕金森病评定量表、霍恩和亚尔分级（HY）、施瓦布和英格兰量表、简易精神状态检查以及医院焦虑抑郁量表对患者进行评估。使用MOS简明健康调查36项量表（SF-36）、PDQ-39和SCOPA-PS对健康相关生活质量进行评估。纳入了144例患者（平均年龄62岁；男性占53.5%；平均病程6.6年；HY分级为1-4级）。SCOPA-PS和PDQ-39总结指数（SI）的平均值分别为39.2和40.7。SCOPA-PS的内部一致性（克朗巴赫α系数=0.84；项目与总分的相关性为0.44-0.73）以及PDQ-39各维度的内部一致性（α系数=0.61-0.85；项目与总分的相关性为0.46-0.82）均令人满意。关于问卷的稳定性，SCOPA-PS的组内相关系数（ICC）值为0.71，PDQ-39 SI的ICC值为0.86。PDQ-39各维度的ICC值范围为0.52（社会支持）至0.80（耻辱感）。PDQ-39各维度的测量标准误（SEM）值范围为0.49（情绪健康）至17.52（社会支持）。SCOPA-PS和PDQ-39 SI的SEM值分别为11.84和6.72。发现SCOPA-PS和PDQ-39 SI与SF-36身体成分（分别为-0.42和-0.52）和心理成分（-0.41）存在显著相关性。SCOPA-PS和PDQ-39巴西版具有令人满意的计量学属性。
