Lilleby V, Gran J T
Revmatologisk avdeling, Aust-Agder Sentralsjukehus, Arendal.
Tidsskr Nor Laegeforen. 1997 Feb 10;117(4):517-8.
The symptoms and signs of remitting, seronegative symmetrical synovitis with pitting oedema (RS3PE-syndrome) are reviewed. Three patients with the disease are described, of whom one also developed multiple myeloma. All patients presented with diffuse swelling of the hands, consisting of both arthritis and oedema. Radiological examination did not disclose erosive changes, and all patients recovered. The article includes recommendations for clinical and laboratory investigations and therapy. The condition usually has a favourable outcome.
回顾了伴有凹陷性水肿的缓解性血清阴性对称性滑膜炎（RS3PE综合征）的症状和体征。描述了3例患有该疾病的患者，其中1例还发展为多发性骨髓瘤。所有患者均表现为手部弥漫性肿胀，包括关节炎和水肿。放射学检查未发现侵蚀性改变，所有患者均康复。本文包括临床和实验室检查及治疗的建议。该疾病通常预后良好。
