Hughes C A, Proctor L
Department of Otolaryngology-Head and Neck Surgery, Georgetown University Medical Center, Washington, D.C., U.S.A.
Laryngoscope. 1997 May;107(5):607-13. doi: 10.1097/00005537-199705000-00010.
Benign paroxysmal positional vertigo (BPPV) has received renewed clinical interest. At the Johns Hopkins Otological Vestibular Laboratory, 781 patients were tested on more than one occasion between September 1976 and November 1992. Of these patients, 187 (24%) were found to have positional nystagmus consistent with a diagnosis of BPPV. A retrospective analysis of these patients' records, including vestibular test and eye movement reports, audiograms, questionnaires, and hospital charts was performed. After this review, the nystagmus, initially diagnosed as due to BPPV, was believed to be a manifestation of another disease process in 36 cases. Of the remaining 151 cases, 52 (34%) presented with no significant preceding disorder and have been termed primary BPPV. In the remaining 99 patients we found coexisting or associated disorders which included Meniere's disease, head trauma, prior ear surgery, vestibular neuronitis, migraine, and others. Forty-five of these 151 patients (31%) had an associated diagnosis of Meniere's disease. To our knowledge a significant association between Meniere's disease and BPPV has not been reported. A review of the literature with discussion of BPPV and the associated disorders is offered.
良性阵发性位置性眩晕（BPPV）重新引起了临床关注。在约翰霍普金斯耳科前庭实验室，1976年9月至1992年11月期间，对781例患者进行了多次测试。在这些患者中，187例（24%）被发现有符合BPPV诊断的位置性眼球震颤。对这些患者的记录进行了回顾性分析，包括前庭测试和眼动报告、听力图、问卷以及医院病历。经过此次审查，最初诊断为BPPV所致的眼球震颤，在36例中被认为是另一种疾病过程的表现。在其余151例中，52例（34%）无明显的前驱疾病，被称为原发性BPPV。在其余99例患者中，我们发现了并存或相关的疾病，包括梅尼埃病、头部外伤、既往耳部手术、前庭神经炎、偏头痛等。这151例患者中有45例（31%）伴有梅尼埃病诊断。据我们所知，尚未有关于梅尼埃病与BPPV之间存在显著关联的报道。本文提供了一篇关于BPPV及相关疾病的文献综述并进行了讨论。
