Mupanomunda O K, Alter B P
Division of Pediatric Hematology/Oncology, University of Texas Medical Branch, Galveston 77555-0361, USA.
J Pediatr Hematol Oncol. 1997 Mar-Apr;19(2):165-7. doi: 10.1097/00043426-199703000-00015.
The diagnosis of transient erythroblastopenia of childhood (TEC) is usually straightforward, with temporary cessation of red blood cell production resulting in normocytic normochromic anemia, reticulocytopenia, and bone marrow erythroblastopenia. We describe here a case of TEC presenting with features of leukoerythroblastic anemia. To our knowledge, this is the first such report for TEC.
The case of a 1-year-old girl is described who had a leukoerythroblastic anemia. Bone marrow examination and clinical course indicated that the anemia had a benign etiology-TEC.
The patient presented with anemia, leukocytosis, and a left shift, with metamyelocytes, myelocytes, myeloblasts, and nucleated red cells in the circulation. There was no apparent viral etiology, and the bone marrow aspirate findings were consistent with a recovering marrow. After transfusion, the patient had an uneventful recovery from TEC.
TEC can cause leukoerythroblastic anemia. TEC with this presentation is clinically similar to TEC without leukoerythroblastosis, but other causes of leukoerythroblastosis need to be excluded.
儿童暂时性红细胞生成减少症（TEC）的诊断通常较为直接，红细胞生成暂时停止会导致正细胞正色素性贫血、网织红细胞减少和骨髓成红细胞减少。我们在此描述一例表现为幼粒-幼红细胞性贫血特征的TEC病例。据我们所知，这是首例关于TEC的此类报告。
描述了一名1岁患幼粒-幼红细胞性贫血女孩的病例。骨髓检查和临床病程表明该贫血病因良性——TEC。
患者表现为贫血、白细胞增多和核左移，循环中有晚幼粒细胞、中幼粒细胞、原始粒细胞和有核红细胞。无明显病毒病因，骨髓穿刺结果与正在恢复的骨髓相符。输血后，患者从TEC平稳康复。
TEC可导致幼粒-幼红细胞性贫血。这种表现的TEC在临床上与无幼粒-幼红细胞增多症的TEC相似，但需要排除幼粒-幼红细胞增多症的其他病因。
