Zerjal T, Dashnyam B, Pandya A, Kayser M, Roewer L, Santos F R, Schiefenhövel W, Fretwell N, Jobling M A, Harihara S, Shimizu K, Semjidmaa D, Sajantila A, Salo P, Crawford M H, Ginter E K, Evgrafov O V, Tyler-Smith C
Department of Biochemistry, University of Oxford, United Kingdom.
Am J Hum Genet. 1997 May;60(5):1174-83.
We have identified a new T-->C transition on the human Y chromosome. C-allele chromosomes have been found only in a subset of the populations from Asia and northern Europe and reach their highest frequencies in Yakut, Buryats, and Finns. Examination of the microsatellite haplotypes of the C-allele chromosomes suggests that the mutation occurred recently in Asia. The Y chromosome thus provides both information about population relationships in Asia and evidence for a substantial paternal genetic contribution of Asians to northern European populations such as the Finns.
我们在人类Y染色体上发现了一个新的T→C转换。仅在亚洲和北欧部分人群中发现了C等位基因染色体，在雅库特人、布里亚特人和芬兰人中其频率最高。对C等位基因染色体微卫星单倍型的检测表明，该突变最近发生在亚洲。因此，Y染色体既提供了有关亚洲人群关系的信息，也为亚洲人对芬兰等北欧人群有大量父系基因贡献提供了证据。
