Bovenzi M, Griffin M J, Ruffell C M
Institute of Occupational Health, University of Trieste, Centro Tumori, Italy.
Cent Eur J Public Health. 1995;3 Suppl:15-8.
The aim of this experimental study was to investigate the pathophysiological mechanisms involved in the acute effects of unilateral vibration on the digital circulation of healthy men. In the fingers of both hands of eight male subjects (age 23-47 years) who had never worked with vibrating tools, finger blood flow (FBF) and finger skin temperature (FST) in thermoneutral conditions, and the percentage change of finger systolic pressure (FSP %) after local cooling from 30 to 10 degrees C were measured. The right hand was exposed for 30 min to sinusoidal vibration with a frequency of 125 Hz and an acceleration of 87.5 m.s.-2r.m.s. A control condition consisted of exposure to the same static load (10 N) but without vibration. The measures of digital circulation were taken before exposure to vibration and static load and at 0, 30, 60, and 90 min after the end of each exposure. Exposure to static load caused no significant changes in FBF, FST, or FSP % in either the test right or the control left finger. Immediately after vibration, there was a temporary increase in FBF in the vibrated right finger, while the non-vibrated left finger exhibited no vasodilation. In both the vibrated and non-vibrated fingers, FBF and FST significantly reduced during the recovery time. A large inter-subject variability was observed for FBF and, to a lesser extent, for FST. In the vibrated right finger the decrease in blood flow was significantly related to cold-induced vasoconstriction in the digital vessels. Such a relation was not observed in the non-vibrated left finger. The results of this investigation suggest that acute vibration can disturb the function of digital vessels through two different and opposite mechanisms. Vibration appears to produce local vasodilation and to trigger a central sympathetic reflex vasoconstriction which can be recorded in the ipsilateral and the contralateral finger to vibration. Both local and central vasoconstrictor mechanisms are likely to be involved in the response to cold observed in the digital vessels of a vibrated finger.
本实验研究的目的是探究单侧振动对健康男性手指循环急性影响所涉及的病理生理机制。在8名（年龄23 - 47岁）从未使用过振动工具的男性受试者双手手指中，测量了其在热中性条件下的手指血流量（FBF）、手指皮肤温度（FST），以及从30℃局部冷却至10℃后手指收缩压的变化百分比（FSP%）。右手暴露于频率为125Hz、加速度为87.5m·s⁻²均方根值的正弦振动下30分钟。对照条件为暴露于相同的静态负荷（10N）但无振动。在暴露于振动和静态负荷之前以及每次暴露结束后的0、30、60和90分钟时，进行手指循环的测量。暴露于静态负荷下，测试的右手手指和对照的左手手指的FBF、FST或FSP%均未出现显著变化。振动后立即出现振动的右手手指的FBF暂时增加，而未振动的左手手指未出现血管舒张。在振动和未振动的手指中，恢复期间FBF和FST均显著降低。观察到FBF存在较大的个体间变异性，FST的个体间变异性较小。在振动的右手手指中，血流减少与手指血管中冷诱导的血管收缩显著相关。在未振动的左手手指中未观察到这种关系。本研究结果表明，急性振动可通过两种不同且相反的机制干扰手指血管的功能。振动似乎会产生局部血管舒张并引发中枢交感反射性血管收缩，这在振动手指的同侧和对侧手指中均可记录到。局部和中枢血管收缩机制可能都参与了振动手指的手指血管对寒冷的反应。
