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9号染色体的C带多态性:通过着丝粒带进行定量分析

C-band polymorphisms of chromosome 9: quantification by Ce-bands.

作者信息

Wahedi K, Pawlowitzki I H

出版信息

Hum Genet. 1987 Sep;77(1):1-5. doi: 10.1007/BF00284704.

DOI:10.1007/BF00284704
PMID:3623557
Abstract

C-band polymorphisms of chromosome 1 can be quantified by Ce bands visualized using oblique epi-illumination. In this paper the polymorphic region of chromosome 9, including variants such as 9qh+, inversions, and translocations, was analyzed in a total of 1860 chromosomes from 20 individuals and 8 fetuses. In this sample we found between zero and five Ce bands on 9q and between zero and four Ce bands on 9p with a maximum of five Ce bands per chromosome. On the basis of these observations at least 19 different polymorphic patterns can be expected theoretically, 15 of which were observed in our sample. Among these, five polymorphic Ce-band classes were distinguishable by the method presented. Considering both homologues, 5(2) = 25 quantitatively discernible chromosome 9 pairs may exist.

摘要

1号染色体的C带多态性可通过斜射落射照明下观察到的Ce带进行定量分析。本文对20名个体和8名胎儿共1860条染色体的9号染色体多态性区域进行了分析,包括9qh+、倒位和易位等变异。在这个样本中,我们发现9q上有0至5条Ce带,9p上有0至4条Ce带,每条染色体最多有5条Ce带。基于这些观察结果,理论上至少可以预期19种不同的多态性模式,其中15种在我们的样本中被观察到。在这些模式中,有5种多态性Ce带类别可通过所提出的方法区分。考虑到两条同源染色体,可能存在5(2)=25种可定量辨别的9号染色体对。

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本文引用的文献

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Pericentric inversion of chromosome 9 in couples with repeated spontaneous abortion.反复自然流产夫妇的9号染色体臂间倒位
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Quantification of C-band polymorphisms by centromeric elevations (Ce-bands).通过着丝粒升高(C带)对C带多态性进行定量分析。
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Quantitative analysis of C bands in chromosomes 1, 9, and 16 of Brazilian Indians and Caucasoids.巴西印第安人和高加索人1号、9号及16号染色体C带的定量分析。
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Individual variation of centric heterochromatin in man.人类着丝粒异染色质的个体差异。
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Aspects of evaluation, significance, and evolution of human C-band heteromorphism.人类C带异态性的评估、意义及进化方面
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